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R G Moran

Showing results (61-70 of 75) with videos related to

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Journal of Medicinal Chemistry|July 1, 1985
Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterinE C Taylor, P J Harrington, S R Fletcher, et al.
NCI Monographs : a Publication of the National Cancer Institute|January 1, 1987
Synthesis and biologic activity of new side-chain-altered methotrexate and aminopterin analogs with dual inhibitory action against dihydrofolate reductase and folylpolyglutamate synthetaseA Rosowsky, R G Moran, J H Freisheim, et al.
Journal of Medicinal Chemistry|October 1, 1986
Methotrexate analogues. 29. Effect of gamma-aminobutyric acid spacers between the pteroyl and glutamate moieties on enzyme binding and cell growth inhibitionA Rosowsky, R A Forsch, J H Freisheim, et al.
Molecular Pharmacology|February 1, 1994
A strategy for the design of membrane-permeable folypoly-gamma-glutamate synthetase inhibitors: "bay-region"-substituted 2-desamino-2-methyl-5,8-dideazafolate analogsP C Sanghani, A Jackman, V R Evans, et al.
Cancer Research|May 15, 1996
Augmentation of the therapeutic activity of lometrexol -(6-R)5,10-dideazatetrahydrofolate- by oral folic acidT Alati, J F Worzalla, C Shih, et al.
Biochemistry|February 19, 1991
Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferaseS W Baldwin, A Tse, L S Gossett, et al.
Cancer Research|September 1, 1990
Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivoA L Jackman, G A Taylor, B M O'Connor, et al.
Cancer Research|January 8, 2000
Tissue-specific expression of functional isoforms of mouse folypoly-gamma-glutamae synthetase: a basis for targeting folate antimetabolitesF B Turner, J L Andreassi 2nd, J Ferguson, et al.
Journal of Medicinal Chemistry|May 1, 1986
Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chainA Rosowsky, J H Freisheim, R G Moran, et al.
Advances in Enzyme Regulation|January 1, 1991
Thymidylate synthase inhibitors: the in vitro activity of a series of heterocyclic benzoyl ring modified 2-desamino-2-methyl-N10-substituted-5,8-dideazafolatesA L Jackman, P R Marsham, R G Moran, et al.
Pageof 8

Showing results (61-70 of 75) with videos related to

Sort By:
Pageof 8
Journal of Medicinal Chemistry|July 1, 1985
Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterinE C Taylor, P J Harrington, S R Fletcher, et al.
NCI Monographs : a Publication of the National Cancer Institute|January 1, 1987
Synthesis and biologic activity of new side-chain-altered methotrexate and aminopterin analogs with dual inhibitory action against dihydrofolate reductase and folylpolyglutamate synthetaseA Rosowsky, R G Moran, J H Freisheim, et al.
Journal of Medicinal Chemistry|October 1, 1986
Methotrexate analogues. 29. Effect of gamma-aminobutyric acid spacers between the pteroyl and glutamate moieties on enzyme binding and cell growth inhibitionA Rosowsky, R A Forsch, J H Freisheim, et al.
Molecular Pharmacology|February 1, 1994
A strategy for the design of membrane-permeable folypoly-gamma-glutamate synthetase inhibitors: "bay-region"-substituted 2-desamino-2-methyl-5,8-dideazafolate analogsP C Sanghani, A Jackman, V R Evans, et al.
Cancer Research|May 15, 1996
Augmentation of the therapeutic activity of lometrexol -(6-R)5,10-dideazatetrahydrofolate- by oral folic acidT Alati, J F Worzalla, C Shih, et al.
Biochemistry|February 19, 1991
Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferaseS W Baldwin, A Tse, L S Gossett, et al.
Cancer Research|September 1, 1990
Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivoA L Jackman, G A Taylor, B M O'Connor, et al.
Cancer Research|January 8, 2000
Tissue-specific expression of functional isoforms of mouse folypoly-gamma-glutamae synthetase: a basis for targeting folate antimetabolitesF B Turner, J L Andreassi 2nd, J Ferguson, et al.
Journal of Medicinal Chemistry|May 1, 1986
Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chainA Rosowsky, J H Freisheim, R G Moran, et al.
Advances in Enzyme Regulation|January 1, 1991
Thymidylate synthase inhibitors: the in vitro activity of a series of heterocyclic benzoyl ring modified 2-desamino-2-methyl-N10-substituted-5,8-dideazafolatesA L Jackman, P R Marsham, R G Moran, et al.
Pageof 8