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Proceedings of the National Academy of Sciences of the United States of America|June 18, 2026
Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairmentMatasha Dhar, Edwin Vázquez-Rosa, Kalyani Chaubey, et al.Journal of Medicinal Chemistry|January 4, 2018
Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune DiseasesMichael L Vazquez, Neelu Kaila, Joseph W Strohbach, et al.The Journal of Clinical Investigation|November 9, 2020
YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stressElisa De Franco, Maria Lytrivi, Hazem Ibrahim, et al.Bioorganic & Medicinal Chemistry Letters|August 16, 2012
Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infectionsMark J Mitton-Fry, Joel T Arcari, Matthew F Brown, et al.Proceedings of the National Academy of Sciences of the United States of America|February 6, 2010
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesisIntza Garin, Emma L Edghill, Ildem Akerman, et al.Cell Reports. Medicine|December 23, 2025
Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brainKalyani Chaubey, Edwin Vázquez-Rosa, Sunil Jamuna Tripathi, et al.Journal of Medicinal Chemistry|June 6, 2013
Discovery of Dap-3 polymyxin analogues for the treatment of multidrug-resistant Gram-negative nosocomial infectionsThomas V Magee, Matthew F Brown, Jeremy T Starr, et al.Research Square|August 13, 2025
Cross-tissue omics-guided drug repurposing triangulates novel targetable mechanisms for Alzheimer's disease and candidate genetic biomarkers for treatment stratificationSathyaseelan Chakkarai, Michal Sadowski, Qiong Yang, et al.Brain : a Journal of Neurology|May 1, 2019
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group reportPeter T Nelson, Dennis W Dickson, John Q Trojanowski, et al.Journal of the American Society of Nephrology : JASN|April 5, 2017
Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2Oscar Rubio Cabezas, Sarah E Flanagan, Horia Stanescu, et al.Pageof 51