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Nucleic Acids Research|September 4, 2024
Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiencyJianfeng Chen, Siyuan Su, Adrian Pickar-Oliver, et al.ACS Chemical Biology|August 20, 2021
A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH ComplexJarod M Waybright, Sarah E Clinkscales, Kimberly D Barnash, et al.ACS Pharmacology & Translational Science|October 16, 2025
A First-in-Class Chemical-Induced Proximity System Achieves Dose-Dependent Control of Tumor Protein P53 Gene Activation in Preclinical Models of Gastric CancerTravis J Nelson, Ryan M Kemper, Anna M Chiarella, et al.Nature Genetics|December 1, 2019
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcomaBerkley E Gryder, Silvia Pomella, Carly Sayers, et al.Cancer Discovery|February 16, 2021
PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic VulnerabilityJason R Pitarresi, Robert J Norgard, Anna M Chiarella, et al.Genes & Development|March 19, 2021
Mutant p53 regulates Survivin to foster lung metastasisQiaosi Tang, Gizem Efe, Anna M Chiarella, et al.The Oncologist|February 22, 2023
Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic CancerKimberly Perez, Anna M Chiarella, James M Cleary, et al.Pageof 6