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Bioorganic & Medicinal Chemistry Letters|May 18, 2007
Alpha-methylation at benzylic fragment of N-aryl-N'-benzyl ureas provides TRPV1 antagonists with better pharmacokinetic properties and higher efficacy in inflammatory pain modelArthur Gomtsyan, Erol K Bayburt, Ryan Keddy, et al.
Pain|July 13, 2010
A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain modelPamela S Puttfarcken, Ping Han, Shailen K Joshi, et al.
Plos Pathogens|October 27, 2017
Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infectionAdam L Bailey, Connor R Buechler, Daniel R Matson, et al.
Bioorganic & Medicinal Chemistry Letters|June 10, 2022
Discovery and SAR of 4-aminopyrrolidine-2-carboxylic acid correctors of CFTR for the treatment of cystic fibrosisMarc J C Scanio, Xenia B Searle, Bo Liu, et al.
ACS Medicinal Chemistry Letters|November 22, 2019
Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic FibrosisMarc J C Scanio, Xenia B Searle, Bo Liu, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivityGuo Zhu Zheng, Yue Mao, Chih-Hung Lee, et al.
Blood Cancer Discovery|July 9, 2025
An Isoform-Specific RUNX1C-BTG2 Axis Governs AML Quiescence and ChemoresistanceCuijuan Han, Zhiping Zhang, Edie I Crosse, et al.
Plos Pathogens|August 7, 2023
Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus macaque (Macaca mulatta) modelMichelle R Koenig, Ann M Mitzey, Xiankun Zeng, et al.
Biorxiv : the Preprint Server for Biology|December 15, 2025
Ultrafast CTCF dynamics control cohesin barrier functionSergei Rudnizky, Peter J Murray, Emily W Sørensen, et al.
Cell Chemical Biology|October 7, 2025
Discovery of a tau-aggregate clearing compound that covalently targets P4HBLouis P Conway, Michelle A Estrada, Weichao Li, et al.
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