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R L BLAKLEY

Showing results (31-40 of 79) with videos related to

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Biochemistry|April 14, 1992
Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiencyJ R Appleman, J T Tsay, J H Freisheim, et al.
The Journal of Biological Chemistry|November 25, 1975
Studies on the mechanism of adenosylcobalamin-dependent ribonucleotide reduction by the use of analogs of the coenzymeG N Sando, R L Blakley, H P Hogenkamp, et al.
Cancer Research|March 1, 1994
Pharmacokinetics of cladribine (2-chlorodeoxyadenosine) in children with acute leukemiaC M Kearns, R L Blakley, V M Santana, et al.
Archives of Biochemistry and Biophysics|September 1, 1993
Dihydrofolate reductase from the pathogenic fungus Pneumocystis carinii: catalytic properties and interaction with antifolatesS A Margosiak, J R Appleman, D V Santi, et al.
Archives of Biochemistry and Biophysics|November 1, 1993
13C and 15N nuclear magnetic resonance evidence that the active site carboxyl group of dihydrofolate reductase is not involved in the relay of a proton to substrateR L Blakley, J R Appleman, J H Freisheim, et al.
The Journal of Biological Chemistry|July 5, 1988
Role of aspartate 27 in the binding of methotrexate to dihydrofolate reductase from Escherichia coliJ R Appleman, E E Howell, J Kraut, et al.
Human Gene Therapy|November 14, 1997
A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugsJ Galipeau, E Benaim, H T Spencer, et al.
Biochemical Pharmacology|June 17, 2000
Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3F Giorgianni, P K Bridson, B P Sorrentino, et al.
Advances in Experimental Medicine and Biology|January 1, 1993
Conformational analysis of human dihydrofolate reductase inhibitor complexes: crystal structure determination of wild type and F31 mutant binary and ternary inhibitor complexesV Cody, A Wojtczak, T I Kalman, et al.
Biochimica Et Biophysica Acta|August 24, 1976
Analysis of the electron paramagnetic resonance spectrum of the cobalamin intermediate in ribonucleotide reductionR E Coffman, Y Ishikawa, R L Blakley, et al.
Pageof 8

Showing results (31-40 of 79) with videos related to

Sort By:
Pageof 8
Biochemistry|April 14, 1992
Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiencyJ R Appleman, J T Tsay, J H Freisheim, et al.
The Journal of Biological Chemistry|November 25, 1975
Studies on the mechanism of adenosylcobalamin-dependent ribonucleotide reduction by the use of analogs of the coenzymeG N Sando, R L Blakley, H P Hogenkamp, et al.
Cancer Research|March 1, 1994
Pharmacokinetics of cladribine (2-chlorodeoxyadenosine) in children with acute leukemiaC M Kearns, R L Blakley, V M Santana, et al.
Archives of Biochemistry and Biophysics|September 1, 1993
Dihydrofolate reductase from the pathogenic fungus Pneumocystis carinii: catalytic properties and interaction with antifolatesS A Margosiak, J R Appleman, D V Santi, et al.
Archives of Biochemistry and Biophysics|November 1, 1993
13C and 15N nuclear magnetic resonance evidence that the active site carboxyl group of dihydrofolate reductase is not involved in the relay of a proton to substrateR L Blakley, J R Appleman, J H Freisheim, et al.
The Journal of Biological Chemistry|July 5, 1988
Role of aspartate 27 in the binding of methotrexate to dihydrofolate reductase from Escherichia coliJ R Appleman, E E Howell, J Kraut, et al.
Human Gene Therapy|November 14, 1997
A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugsJ Galipeau, E Benaim, H T Spencer, et al.
Biochemical Pharmacology|June 17, 2000
Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3F Giorgianni, P K Bridson, B P Sorrentino, et al.
Advances in Experimental Medicine and Biology|January 1, 1993
Conformational analysis of human dihydrofolate reductase inhibitor complexes: crystal structure determination of wild type and F31 mutant binary and ternary inhibitor complexesV Cody, A Wojtczak, T I Kalman, et al.
Biochimica Et Biophysica Acta|August 24, 1976
Analysis of the electron paramagnetic resonance spectrum of the cobalamin intermediate in ribonucleotide reductionR E Coffman, Y Ishikawa, R L Blakley, et al.
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