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Bioorganic & Medicinal Chemistry|August 22, 2006
Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based designDésirée H H Tsao, Alan G Sutherland, Lee D Jennings, et al.Nature Reviews. Drug Discovery|December 6, 2019
Rethinking drug design in the artificial intelligence eraPetra Schneider, W Patrick Walters, Alleyn T Plowright, et al.Bioorganic & Medicinal Chemistry Letters|March 10, 2004
Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interactionLee D Jennings, Ken W Foreman, Thomas S Rush, et al.American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons|October 25, 2019
First-in-human clinical trial to assess pharmacokinetics, pharmacodynamics, safety, and tolerability of iscalimab, an anti-CD40 monoclonal antibodyPascal Espié, YanLing He, Phillip Koo, et al.American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons|April 18, 2018
Characterization of the in vitro and in vivo properties of CFZ533, a blocking and non-depleting anti-CD40 monoclonal antibodyJacinda Ristov, Pascal Espie, Peter Ulrich, et al.Proceedings of the National Academy of Sciences of the United States of America|October 27, 2017
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel diseaseElizaveta S Leshchiner, Jason S Rush, Michael A Durney, et al.Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia|November 21, 2023
Efficacy and safety of iscalimab, a novel anti-CD40 monoclonal antibody, in moderate-to-severe myasthenia gravis: A phase 2 randomized studyBaltazar GomezMancilla, Matthew N Meriggioli, Angela Genge, et al.American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons|July 4, 2015
A novel, blocking, Fc-silent anti-CD40 monoclonal antibody prolongs nonhuman primate renal allograft survival in the absence of B cell depletionF Cordoba, G Wieczorek, M Audet, et al.Immunity|October 22, 2015
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal InflammationZhifang Cao, Kara L Conway, Robert J Heath, et al.Science Translational Medicine|September 22, 2021
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchersC Glenn Begley, Mark Ashton, Jonathan Baell, et al.Pageof 26