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The Journal of Biological Chemistry|March 5, 1991
Effect of direct suppression of thymidylate synthase at the 5,10-methylenetetrahydrofolate binding site on the interconversion of tetrahydrofolate cofactors to dihydrofolate by antifolates. Influence of degree of dihydrofolate reductase inhibitionR L Seither, D F Trent, D C Mikulecky, et al.The Journal of Biological Chemistry|October 15, 1989
Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cellsR L Seither, D F Trent, D C Mikulecky, et al.Pageof 2