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Bioorganic & Medicinal Chemistry Letters|June 2, 2009
Substituted benzimidazoles: A novel chemotype for small molecule hKSP inhibitorsBrian R Lahue, Yao Ma, Gerald W Shipps, et al.
Bioorganic & Medicinal Chemistry Letters|February 4, 2014
Substituted piperidines as HDM2 inhibitorsYao Ma, Brian R Lahue, Gerald W Shipps, et al.
The Journal of Organic Chemistry|October 9, 2004
Intramolecular inverse-electron-demand Diels-Alder reactions of imidazoles with 1,2,4-triazines: a new route to 1,2,3,4-tetrahydro-1,5-naphthyridines and related heterocyclesBrian R Lahue, Sie-Mun Lo, Zhao-Kui Wan, et al.
Bioorganic & Medicinal Chemistry Letters|April 16, 2016
Structure-activity relationship study of 4-substituted piperidines at Leu26 moiety of novel p53-hDM2 inhibitorsYuan Tian, Yao Ma, Craig R Gibeau, et al.
Bioorganic & Medicinal Chemistry Letters|March 25, 2014
Core modification of substituted piperidines as novel inhibitors of HDM2-p53 protein-protein interactionWeidong Pan, Brian R Lahue, Yao Ma, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Pivotal Role of an Aliphatic Side Chain in the Development of an HDM2 InhibitorYao Ma, Brian R Lahue, Craig R Gibeau, et al.
Bioorganic & Medicinal Chemistry|December 16, 2019
Diversity & tractability revisited in collaborative small molecule phenotypic screening library designBrian R Lahue, Meir Glick, Matthew Tudor, et al.
Bioorganic & Medicinal Chemistry Letters|February 14, 2022
Phe19 modification of HDM2-p53 PPI inhibitors to alleviate CYP3A4 metabolism/mechanism-based inhibition liabilityYuan Tian, Brian R Lahue, Yao Ma, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 InhibitorsStéphane L Bogen, Weidong Pan, Craig R Gibeau, et al.
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