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Immunity|September 26, 2025
Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4Coral Del Mar Alicea Pauneto, Brian P Riesenberg, Evelyn J Gandy, et al.Cell Host & Microbe|May 21, 2013
The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signalingJin A Cho, Ann-Hwee Lee, Barbara Platzer, et al.Diabetes|December 29, 2019
De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic DysfunctionElisa De Franco, Richard Caswell, Matthew B Johnson, et al.Diabetes|July 10, 2012
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosisDaniel A Cunha, Mariana Igoillo-Esteve, Esteban N Gurzov, et al.Diabetes|July 11, 2015
A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and MicrocephalyBaroj Abdulkarim, Marc Nicolino, Mariana Igoillo-Esteve, et al.Nature|August 27, 2005
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2Mauro Costa-Mattioli, Delphine Gobert, Heather Harding, et al.Proceedings of the National Academy of Sciences of the United States of America|January 30, 2013
Role for the obesity-related FTO gene in the cellular sensing of amino acidsPawan Gulati, Man Ka Cheung, Robin Antrobus, et al.The Journal of Biological Chemistry|August 12, 2011
Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolismAndreas L Birkenfeld, Hui-Young Lee, Sachin Majumdar, et al.Journal of Biomolecular Screening|August 17, 2011
Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein responseAndrew M Fribley, Patricia G Cruz, Justin R Miller, et al.The Journal of Experimental Medicine|January 14, 2017
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitisMarkus Tschurtschenthaler, Timon E Adolph, Jonathan W Ashcroft, et al.Pageof 37