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Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 16, 2016
Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug ConjugatesDonglu Zhang, Shang-Fan Yu, Yong Ma, et al.Molecular Cancer Therapeutics|December 4, 2020
An Anti-CD22-seco-CBI-Dimer Antibody-Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical ModelsShang-Fan Yu, Donna W Lee, Bing Zheng, et al.Journal of the American Chemical Society|July 1, 2024
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to TherapyPragya Adhikari, Guangmin Li, MaryAnn Go, et al.Science (New York, N.Y.)|March 21, 2020
Evolving epidemiology of poliovirus serotype 2 following withdrawal of the serotype 2 oral poliovirus vaccineG R Macklin, K M O'Reilly, N C Grassly, et al.Bioconjugate Chemistry|January 26, 2018
Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing PayloadsDonglu Zhang, Hoa Le, Josefa Dela Cruz-Chuh, et al.ACS Medicinal Chemistry Letters|November 25, 2016
Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody-Drug ConjugatesDonglu Zhang, Thomas H Pillow, Yong Ma, et al.Bioconjugate Chemistry|June 22, 2017
Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug ConjugatesJack D Sadowsky, Thomas H Pillow, Jinhua Chen, et al.Chemmedchem|November 2, 2019
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo ActivityThomas H Pillow, Pragya Adhikari, Robert A Blake, et al.Journal of Medicinal Chemistry|February 17, 2021
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular PropertiesPeter S Dragovich, Thomas H Pillow, Robert A Blake, et al.Journal of Medicinal Chemistry|February 17, 2021
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor EfficacyPeter S Dragovich, Thomas H Pillow, Robert A Blake, et al.Pageof 12