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Journal of Medicinal Chemistry
|
June 15, 2017
A Highly Selective Hydantoin Inhibitor of Aggrecanase-1 and Aggrecanase-2 with a Low Projected Human Dose
Timothy B Durham, Jothirajah Marimuthu, James L Toth, et al.
Journal of Medicinal Chemistry
|
May 20, 2016
Use of Osmotic Pumps to Establish the Pharmacokinetic-Pharmacodynamic Relationship and Define Desirable Human Performance Characteristics for Aggrecanase Inhibitors
Michael R Wiley, Timothy B Durham, Lisa A Adams, et al.
Journal of Medicinal Chemistry
|
May 1, 2012
Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor
Concepción Pedregal, Elizabeth M Joshi, Miguel A Toledo, et al.
Journal of Medicinal Chemistry
|
April 1, 2014
Discovery of a novel series of orally active nociceptin/orphanin FQ (NOP) receptor antagonists based on a dihydrospiro(piperidine-4,7'-thieno[2,3-c]pyran) scaffold
Miguel A Toledo, Concepción Pedregal, Celia Lafuente, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 19, 2003
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes
Ajay Madan, Richard A Graham, Kathleen M Carroll, et al.
Drug Discovery Today
|
May 7, 2017
Translational pharmacokinetic-pharmacodynamic analysis in the pharmaceutical industry: an IQ Consortium PK-PD Discussion Group perspective
Harvey Wong, Tonika Bohnert, Valeriu Damian-Iordache, et al.
ACS Medicinal Chemistry Letters
|
September 24, 2016
Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design
Spencer B Jones, Lance A Pfeifer, Thomas J Bleisch, et al.
The AAPS Journal
|
January 30, 2015
Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape
Edgar Schuck, Tonika Bohnert, Arijit Chakravarty, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 14, 2017
Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1
Katherine M Partridge, Stephen Antonysamy, Shobha N Bhattachar, et al.
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of 2
Search research articles
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Showing results (11-20 of 19) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 19 results.
Journal of Medicinal Chemistry
|
June 15, 2017
A Highly Selective Hydantoin Inhibitor of Aggrecanase-1 and Aggrecanase-2 with a Low Projected Human Dose
Timothy B Durham, Jothirajah Marimuthu, James L Toth, et al.
Journal of Medicinal Chemistry
|
May 20, 2016
Use of Osmotic Pumps to Establish the Pharmacokinetic-Pharmacodynamic Relationship and Define Desirable Human Performance Characteristics for Aggrecanase Inhibitors
Michael R Wiley, Timothy B Durham, Lisa A Adams, et al.
Journal of Medicinal Chemistry
|
May 1, 2012
Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor
Concepción Pedregal, Elizabeth M Joshi, Miguel A Toledo, et al.
Journal of Medicinal Chemistry
|
April 1, 2014
Discovery of a novel series of orally active nociceptin/orphanin FQ (NOP) receptor antagonists based on a dihydrospiro(piperidine-4,7'-thieno[2,3-c]pyran) scaffold
Miguel A Toledo, Concepción Pedregal, Celia Lafuente, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 19, 2003
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes
Ajay Madan, Richard A Graham, Kathleen M Carroll, et al.
Drug Discovery Today
|
May 7, 2017
Translational pharmacokinetic-pharmacodynamic analysis in the pharmaceutical industry: an IQ Consortium PK-PD Discussion Group perspective
Harvey Wong, Tonika Bohnert, Valeriu Damian-Iordache, et al.
ACS Medicinal Chemistry Letters
|
September 24, 2016
Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design
Spencer B Jones, Lance A Pfeifer, Thomas J Bleisch, et al.
The AAPS Journal
|
January 30, 2015
Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape
Edgar Schuck, Tonika Bohnert, Arijit Chakravarty, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 14, 2017
Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1
Katherine M Partridge, Stephen Antonysamy, Shobha N Bhattachar, et al.
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of 2