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British Journal of Anaesthesia|December 6, 1997
A physiological model of induction of anaesthesia with propofol in sheep. 2. Model analysis and implications for dose requirementsG L Ludbrook, R N UptonClinical and Experimental Pharmacology & Physiology|July 1, 1999
Kinetic aspects of drug disposition in the lungsR N Upton, D J DooletteClinical Pharmacology and Therapeutics|May 18, 2007
Using disease progression models as a tool to detect drug effectD R Mould, N G Denman, S DuffullXenobiotica; the Fate of Foreign Compounds in Biological Systems|February 24, 2001
Skeletal muscle kinetics of propofol in anaesthetized sheep: effect of altered muscle blood flowD Zheng, R N Upton, A MartinezAnaesthesia and Intensive Care|April 21, 2001
The cerebral and systemic kinetics of thiopentone and propofol in halothane anaesthetized sheepR N Upton, G L Ludbrook, C GrantActa Physiologica Scandinavica|July 27, 2001
Diffusion-limited tissue equilibration and arteriovenous diffusion shunt describe skeletal muscle nitrous oxide kinetics at high and low blood flows in sheepD J Doolette, R N Upton, D ZhengCPT: Pharmacometrics & Systems Pharmacology|July 31, 2015
Interactive Pharmacometric Applications Using R and the Shiny PackageJ Wojciechowski, A M Hopkins, R N UptonClinical and Experimental Pharmacology & Physiology|July 20, 2000
In vivo manipulation and continuous measurement of muscle blood flow with venous effluent samplingD Zheng, D J Doolette, R N UptonJournal of Pharmacokinetics and Biopharmaceutics|September 15, 1999
Diffusion-limited, but not perfusion-limited, compartmental models describe cerebral nitrous oxide kinetics at high and low cerebral blood flowsD J Doolette, R N Upton, C GrantBritish Journal of Anaesthesia|October 3, 2009
Comparison of the sedative properties of CNS 7056, midazolam, and propofol in sheepR N Upton, A M Martinez, C GrantPageof 11