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Aging and Disease|January 6, 2017
Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's DiseaseNatalya A Smirnova, Navneet Ammal Kaidery, Dmitry M Hushpulian, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 22, 2010
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathwayRenée E Haskew-Layton, Jimmy B Payappilly, Natalya A Smirnova, et al.
Molecular Oncology|September 21, 2025
Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolismAdrien M Vaquié, Davod R Shah, Eliane E S Brechbühl, et al.
Annals of Neurology|October 9, 2018
N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E<sub>2</sub> to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in miceSaravanan S Karuppagounder, Lauren Alin, Yingxin Chen, et al.
Annals of the New York Academy of Sciences|December 17, 2008
Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injuryRajiv R Ratan, Ambreena Siddiq, Leila Aminova, et al.
ACS Chemical Biology|April 9, 2014
A selective phenelzine analogue inhibitor of histone demethylase LSD1Polina Prusevich, Jay H Kalin, Shonoi A Ming, et al.
Acta Neuropathologica Communications|January 23, 2023
Parkin coregulates glutathione metabolism in adult mammalian brainDaniel N El Kodsi, Jacqueline M Tokarew, Rajib Sengupta, et al.
EMBO Molecular Medicine|July 29, 2010
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington diseaseStephen J McConoughey, Manuela Basso, Zoya V Niatsetskaya, et al.
Neuron|October 1, 2024
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy modelGillian K Carling, Li Fan, Nessa R Foxe, et al.
Nature Neuroscience|April 24, 2023
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilienceJoe C Udeochu, Sadaf Amin, Yige Huang, et al.
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