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Journal of Medicinal Chemistry
|
December 17, 2025
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy In Vivo
Priyadarshini Jaishankar, Galen J Correy, Yusuke Matsui, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 1, 2026
Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern
Nicole L Inniss, Margarita Rzhetskaya, Ryan P Kich, et al.
Biorxiv : the Preprint Server for Biology
|
November 24, 2025
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy in vivo
Priyadarshini Jaishankar, Galen J Correy, Yusuke Matsui, et al.
Plos One
|
December 11, 2012
Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6
Christopher E Heise, Jeremy Murray, Katherine E Augustyn, et al.
Beilstein Journal of Organic Chemistry
|
February 13, 2013
Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target
Jonathan W Choy, Clifford Bryant, Claudia M Calvet, et al.
Cell Chemical Biology
|
July 30, 2019
Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
Dagmar E Ehrnhoefer, Niels H Skotte, Jeanette Reinshagen, et al.
Biorxiv : the Preprint Server for Biology
|
January 9, 2026
Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens
Jongbin Kim, Galen J Correy, Brendan W Hall, et al.
Biorxiv : the Preprint Server for Biology
|
July 7, 2022
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 Macrodomain of SARS-CoV-2
Stefan Gahbauer, Galen J Correy, Marion Schuller, et al.
Science Advances
|
August 8, 2025
Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance
Matthew T Klope, Poulami Talukder, Brian R Blank, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 4, 2023
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2
Stefan Gahbauer, Galen J Correy, Marion Schuller, et al.
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Search research articles
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Showing results (131-140 of 149) with videos related to
Sort By:
Page
of 15
Journal of Medicinal Chemistry
|
December 17, 2025
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy In Vivo
Priyadarshini Jaishankar, Galen J Correy, Yusuke Matsui, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 1, 2026
Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern
Nicole L Inniss, Margarita Rzhetskaya, Ryan P Kich, et al.
Biorxiv : the Preprint Server for Biology
|
November 24, 2025
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy in vivo
Priyadarshini Jaishankar, Galen J Correy, Yusuke Matsui, et al.
Plos One
|
December 11, 2012
Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6
Christopher E Heise, Jeremy Murray, Katherine E Augustyn, et al.
Beilstein Journal of Organic Chemistry
|
February 13, 2013
Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target
Jonathan W Choy, Clifford Bryant, Claudia M Calvet, et al.
Cell Chemical Biology
|
July 30, 2019
Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
Dagmar E Ehrnhoefer, Niels H Skotte, Jeanette Reinshagen, et al.
Biorxiv : the Preprint Server for Biology
|
January 9, 2026
Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens
Jongbin Kim, Galen J Correy, Brendan W Hall, et al.
Biorxiv : the Preprint Server for Biology
|
July 7, 2022
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 Macrodomain of SARS-CoV-2
Stefan Gahbauer, Galen J Correy, Marion Schuller, et al.
Science Advances
|
August 8, 2025
Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance
Matthew T Klope, Poulami Talukder, Brian R Blank, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 4, 2023
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2
Stefan Gahbauer, Galen J Correy, Marion Schuller, et al.
Page
of 15