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Nature Medicine|June 1, 2026
SEZ6-targeting antibody-drug conjugate ABBV-706 in advanced small cell lung cancer and solid tumors: a phase 1 trialLauren Averett Byers, Byoung Chul Cho, Alissa J Cooper, et al.
Biorxiv : the Preprint Server for Biology|April 2, 2024
CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic LethalityJean Ching-Yi Tien, Yu Chang, Yuping Zhang, et al.
Cell Reports. Medicine|October 5, 2024
CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13Jean Ching-Yi Tien, Jie Luo, Yu Chang, et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics|November 17, 2017
Characterizing reduced coverage regions through comparison of exome and genome sequencing data across 10 centersRashesh V Sanghvi, Christian J Buhay, Bradford C Powell, et al.
Nature|August 8, 2017
Integrative clinical genomics of metastatic cancerDan R Robinson, Yi-Mi Wu, Robert J Lonigro, et al.
Journal of Medicinal Chemistry|October 6, 2022
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase ThetaMartin L Stockley, Amanda Ferdinand, Giovanni Benedetti, et al.
Journal of Medicinal Chemistry|December 4, 2024
Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid CancersChristopher L Carroll, Michael G Johnson, Yanbing Ding, et al.
Journal of Pediatric Surgery|August 14, 2025
Non-operative management of pediatric, uncomplicated acute appendicitis: A survey of pediatric surgeons' perceptions and practiceNitin Sajankila, Cecilia Gigena, Kylie Callier, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 13, 2026
The pharmacological profile of ART6043, a first-in-class clinical DNA polymerase theta polymerase domain inhibitor potentiating PARP inhibitor efficacyHelen M R Robinson, Vera Grinkevich, Jayesh B Majithiya, et al.
American Journal of Human Genetics|November 19, 2019
Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male InfertilityPatrick Lorès, Denis Dacheux, Zine-Eddine Kherraf, et al.
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