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R S Alexander

Showing results (41-50 of 51) with videos related to

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Bioorganic & Medicinal Chemistry Letters|June 24, 2000
Synthesis and activity studies of conformationally restricted alpha-ketoamide factor Xa inhibitorsJ Cacciola, J M Fevig, P F Stouten, et al.
Protein Engineering|October 1, 1995
Structure of His94-->Asp carbonic anhydrase II in a new crystalline form reveals a partially occupied zinc binding siteJ A Ippolito, S K Nair, R S Alexander, et al.
Bioorganic & Medicinal Chemistry Letters|January 5, 1999
Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor XaJ M Fevig, J Cacciola, R S Alexander, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 1999
Rational design of boropeptide thrombin inhibitors: beta, beta-dialkyl-phenethylglycine P2 analogs of DuP 714 with greater selectivity over complement factor I and an improved safety profileJ M Fevig, J Buriak, J Cacciola, et al.
Journal of Medicinal Chemistry|July 30, 1999
Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2M L Quan, C D Ellis, A Y Liauw, et al.
Protein Science : a Publication of the Protein Society|January 1, 1994
Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitorsG M Smith, R S Alexander, D W Christianson, et al.
Bioorganic & Medicinal Chemistry Letters|May 7, 1999
Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitorsC Dominguez, D E Duffy, Q Han, et al.
Bioorganic & Medicinal Chemistry Letters|March 4, 2000
The de novo design and synthesis of cyclic urea inhibitors of factor Xa: optimization of the S4 ligandR A Galemmo, B L Wells, K A Rossi, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 1999
Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitorsJ V Duncia, J B Santella, C A Higley, et al.
Journal of Medicinal Chemistry|November 23, 2000
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitorsQ Han, C Dominguez, P F Stouten, et al.
Pageof 6

Showing results (41-50 of 51) with videos related to

Sort By:
Pageof 6
Bioorganic & Medicinal Chemistry Letters|June 24, 2000
Synthesis and activity studies of conformationally restricted alpha-ketoamide factor Xa inhibitorsJ Cacciola, J M Fevig, P F Stouten, et al.
Protein Engineering|October 1, 1995
Structure of His94-->Asp carbonic anhydrase II in a new crystalline form reveals a partially occupied zinc binding siteJ A Ippolito, S K Nair, R S Alexander, et al.
Bioorganic & Medicinal Chemistry Letters|January 5, 1999
Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor XaJ M Fevig, J Cacciola, R S Alexander, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 1999
Rational design of boropeptide thrombin inhibitors: beta, beta-dialkyl-phenethylglycine P2 analogs of DuP 714 with greater selectivity over complement factor I and an improved safety profileJ M Fevig, J Buriak, J Cacciola, et al.
Journal of Medicinal Chemistry|July 30, 1999
Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2M L Quan, C D Ellis, A Y Liauw, et al.
Protein Science : a Publication of the Protein Society|January 1, 1994
Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitorsG M Smith, R S Alexander, D W Christianson, et al.
Bioorganic & Medicinal Chemistry Letters|May 7, 1999
Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitorsC Dominguez, D E Duffy, Q Han, et al.
Bioorganic & Medicinal Chemistry Letters|March 4, 2000
The de novo design and synthesis of cyclic urea inhibitors of factor Xa: optimization of the S4 ligandR A Galemmo, B L Wells, K A Rossi, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 1999
Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitorsJ V Duncia, J B Santella, C A Higley, et al.
Journal of Medicinal Chemistry|November 23, 2000
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitorsQ Han, C Dominguez, P F Stouten, et al.
Pageof 6