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British Journal of Cancer|October 7, 2010
Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapyV Goede, O Coutelle, J Neuneier, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 19, 2009
mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitorHeidi A Lane, Jeanette M Wood, Paul M J McSheehy, et al.Journal of Medicinal Chemistry|September 11, 2007
Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosetsJürgen Maibaum, Stefan Stutz, Richard Göschke, et al.The Journal of Biological Chemistry|March 27, 2014
Fragments of bacterial endoglycosidase s and immunoglobulin g reveal subdomains of each that contribute to deglycosylationEmma V Dixon, Jolyon K Claridge, David J Harvey, et al.Journal of Medicinal Chemistry|December 13, 2002
Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitorsPaul W Manley, Pascal Furet, Guido Bold, et al.Journal of Medicinal Chemistry|September 11, 2007
Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human reninRichard Göschke, Stefan Stutz, Vittorio Rasetti, et al.Biochemical and Biophysical Research Communications|August 21, 2003
Structure-based design of aliskiren, a novel orally effective renin inhibitorJeanette M Wood, Jürgen Maibaum, Joseph Rahuel, et al.Human Molecular Genetics|August 11, 2011
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in miceMartin C Herzig, Carine Kolly, Elke Persohn, et al.Plos Pathogens|August 12, 2020
Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenzaClaire Scott, Jayakanth Kankanala, Toshana L Foster, et al.Acta Crystallographica. Section D, Biological Crystallography|September 27, 2006
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogensM J Fogg, P Alzari, M Bahar, et al.Pageof 12