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R Scott Obach

Showing results (111-120 of 193) with videos related to

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Journal of Clinical Pharmacology|April 8, 2010
Unexpected effect of rifampin on the pharmacokinetics of linezolid: in silico and in vitro approaches to explain its mechanismKuan Gandelman, Tong Zhu, Odette A Fahmi, et al.
Chemical Research in Toxicology|April 3, 2012
Identification of protein targets of reactive metabolites of tienilic acid in human hepatocytesYakov M Koen, Diganta Sarma, Todd D Williams, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 15, 2024
Radiolabel Uncovers Nonintuitive Metabolites of BIIB104: Novel Release of [<sup>14</sup>C]Cyanide from 2-Cyanothiophene and Subsequent Formation of [<sup>14</sup>C]ThiocyanateChungang Gu, Jiansheng Huang, Cathy Muste, et al.
Drugs of Today (Barcelona, Spain : 1998)|March 14, 2007
Varenicline: new treatment with efficacy in smoking cessationVictor I Reus, R Scott Obach, Jotham W Coe, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 30, 2005
The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactionsR Scott Obach, Robert L Walsky, Karthik Venkatakrishnan, et al.
Journal of Medicinal Chemistry|February 26, 2020
Effective Application of Metabolite Profiling in Drug Design and DiscoveryMatthew A Cerny, Amit S Kalgutkar, R Scott Obach, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 24, 2014
Biosynthesis of drug metabolites and quantitation using NMR spectroscopy for use in pharmacologic and drug metabolism studiesGregory S Walker, Jonathan N Bauman, Tim F Ryder, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 30, 2021
Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and HepatocytesElaine Tseng, Heather Eng, Jian Lin, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 17, 2013
Aldehyde oxidase 1 (AOX1) in human liver cytosols: quantitative characterization of AOX1 expression level and activity relationshipCexiong Fu, Li Di, Xiaogang Han, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 27, 2015
Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug MetabolismT Eric Ballard, Shuai Wang, Loretta M Cox, et al.
Pageof 20

Showing results (111-120 of 193) with videos related to

Sort By:
Pageof 20
Journal of Clinical Pharmacology|April 8, 2010
Unexpected effect of rifampin on the pharmacokinetics of linezolid: in silico and in vitro approaches to explain its mechanismKuan Gandelman, Tong Zhu, Odette A Fahmi, et al.
Chemical Research in Toxicology|April 3, 2012
Identification of protein targets of reactive metabolites of tienilic acid in human hepatocytesYakov M Koen, Diganta Sarma, Todd D Williams, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 15, 2024
Radiolabel Uncovers Nonintuitive Metabolites of BIIB104: Novel Release of [<sup>14</sup>C]Cyanide from 2-Cyanothiophene and Subsequent Formation of [<sup>14</sup>C]ThiocyanateChungang Gu, Jiansheng Huang, Cathy Muste, et al.
Drugs of Today (Barcelona, Spain : 1998)|March 14, 2007
Varenicline: new treatment with efficacy in smoking cessationVictor I Reus, R Scott Obach, Jotham W Coe, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 30, 2005
The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactionsR Scott Obach, Robert L Walsky, Karthik Venkatakrishnan, et al.
Journal of Medicinal Chemistry|February 26, 2020
Effective Application of Metabolite Profiling in Drug Design and DiscoveryMatthew A Cerny, Amit S Kalgutkar, R Scott Obach, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 24, 2014
Biosynthesis of drug metabolites and quantitation using NMR spectroscopy for use in pharmacologic and drug metabolism studiesGregory S Walker, Jonathan N Bauman, Tim F Ryder, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 30, 2021
Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and HepatocytesElaine Tseng, Heather Eng, Jian Lin, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 17, 2013
Aldehyde oxidase 1 (AOX1) in human liver cytosols: quantitative characterization of AOX1 expression level and activity relationshipCexiong Fu, Li Di, Xiaogang Han, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 27, 2015
Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug MetabolismT Eric Ballard, Shuai Wang, Loretta M Cox, et al.
Pageof 20