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R Scott Obach

Showing results (151-160 of 193) with videos related to

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Mutation Research|December 5, 2006
Strategy for genotoxicity testing--metabolic considerationsWarren W Ku, Anita Bigger, Giovanni Brambilla, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 16, 2016
An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, et al.
Chemical Research in Toxicology|September 19, 2019
Moving beyond Binary Predictions of Human Drug-Induced Liver Injury (DILI) toward Contrasting Relative Risk PotentialMichael D Aleo, Falgun Shah, Scott Allen, et al.
Journal of Clinical Pharmacology|February 26, 2013
Comprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, part 1: volume of distribution at steady stateFranco Lombardo, Nigel J Waters, Upendra A Argikar, et al.
Journal of Clinical Pharmacology|October 27, 2007
Lack of pharmacokinetic and pharmacodynamic interactions between a smoking cessation therapy, varenicline, and warfarin: an in vivo and in vitro studyAaron H Burstein, David J Clark, Melissa O'Gorman, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 31, 2018
An Ex Vivo Fermentation Screening Platform to Study Drug Metabolism by Human Gut MicrobiotaE van de Steeg, F H J Schuren, R Scott Obach, et al.
European Journal of Medicinal Chemistry|July 31, 2012
Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug designLi Di, Christopher Keefer, Dennis O Scott, et al.
Chemical Research in Toxicology|September 21, 2019
Enzalutamide and Apalutamide: In Vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy ModelChanghua Ji, Mausumee Guha, Xu Zhu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 23, 2011
Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugsRaman Sharma, Timothy J Strelevitz, Hongying Gao, et al.
British Journal of Clinical Pharmacology|February 19, 2008
Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interactionKuresh A Youdim, Aref Zayed, Maurice Dickins, et al.
Pageof 20

Showing results (151-160 of 193) with videos related to

Sort By:
Pageof 20
Mutation Research|December 5, 2006
Strategy for genotoxicity testing--metabolic considerationsWarren W Ku, Anita Bigger, Giovanni Brambilla, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 16, 2016
An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, et al.
Chemical Research in Toxicology|September 19, 2019
Moving beyond Binary Predictions of Human Drug-Induced Liver Injury (DILI) toward Contrasting Relative Risk PotentialMichael D Aleo, Falgun Shah, Scott Allen, et al.
Journal of Clinical Pharmacology|February 26, 2013
Comprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, part 1: volume of distribution at steady stateFranco Lombardo, Nigel J Waters, Upendra A Argikar, et al.
Journal of Clinical Pharmacology|October 27, 2007
Lack of pharmacokinetic and pharmacodynamic interactions between a smoking cessation therapy, varenicline, and warfarin: an in vivo and in vitro studyAaron H Burstein, David J Clark, Melissa O'Gorman, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 31, 2018
An Ex Vivo Fermentation Screening Platform to Study Drug Metabolism by Human Gut MicrobiotaE van de Steeg, F H J Schuren, R Scott Obach, et al.
European Journal of Medicinal Chemistry|July 31, 2012
Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug designLi Di, Christopher Keefer, Dennis O Scott, et al.
Chemical Research in Toxicology|September 21, 2019
Enzalutamide and Apalutamide: In Vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy ModelChanghua Ji, Mausumee Guha, Xu Zhu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 23, 2011
Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugsRaman Sharma, Timothy J Strelevitz, Hongying Gao, et al.
British Journal of Clinical Pharmacology|February 19, 2008
Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interactionKuresh A Youdim, Aref Zayed, Maurice Dickins, et al.
Pageof 20