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R Scott Obach

Showing results (171-180 of 193) with videos related to

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Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 14, 2022
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and HumansHeather Eng, Alyssa L Dantonio, Eugene P Kadar, et al.
The AAPS Journal|October 27, 2023
A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics ApplicationsShiny Amala Priya Rajan, Jason Sherfey, Shivam Ohri, et al.
The AAPS Journal|November 20, 2023
Correction: A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics ApplicationsShiny Amala Priya Rajan, Jason Sherfey, Shivam Ohri, et al.
Lab on a Chip|April 28, 2026
Predicting human pharmacokinetic parameters of drugs using a multi-tissue chip platform integrating liver, kidney, and skeletal muscle microphysiological systemsJason Sherfey, Shiny Amala Priya Rajan, Lauren M Nichols, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|September 14, 2020
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytesChristopher Keefer, George Chang, Anthony Carlo, et al.
Journal of Medicinal Chemistry|May 29, 2020
Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure-Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H<sub>1</sub> Receptor Inverse AgonistManjinder S Lall, Asser Bassyouni, James Bradow, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 11, 2009
The conduct of in vitro studies to address time-dependent inhibition of drug-metabolizing enzymes: a perspective of the pharmaceutical research and manufacturers of AmericaScott W Grimm, Heidi J Einolf, Steven D Hall, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 1, 2018
A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K Chowdhury, et al.
Medicinal Research Reviews|October 24, 2012
The generation, detection, and effects of reactive drug metabolitesAndrew V Stachulski, Thomas A Baillie, B Kevin Park, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 20, 2003
The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspectiveThorir D Bjornsson, John T Callaghan, Heidi J Einolf, et al.
Pageof 20

Showing results (171-180 of 193) with videos related to

Sort By:
Pageof 20
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 14, 2022
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and HumansHeather Eng, Alyssa L Dantonio, Eugene P Kadar, et al.
The AAPS Journal|October 27, 2023
A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics ApplicationsShiny Amala Priya Rajan, Jason Sherfey, Shivam Ohri, et al.
The AAPS Journal|November 20, 2023
Correction: A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics ApplicationsShiny Amala Priya Rajan, Jason Sherfey, Shivam Ohri, et al.
Lab on a Chip|April 28, 2026
Predicting human pharmacokinetic parameters of drugs using a multi-tissue chip platform integrating liver, kidney, and skeletal muscle microphysiological systemsJason Sherfey, Shiny Amala Priya Rajan, Lauren M Nichols, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|September 14, 2020
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytesChristopher Keefer, George Chang, Anthony Carlo, et al.
Journal of Medicinal Chemistry|May 29, 2020
Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure-Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H<sub>1</sub> Receptor Inverse AgonistManjinder S Lall, Asser Bassyouni, James Bradow, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 11, 2009
The conduct of in vitro studies to address time-dependent inhibition of drug-metabolizing enzymes: a perspective of the pharmaceutical research and manufacturers of AmericaScott W Grimm, Heidi J Einolf, Steven D Hall, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 1, 2018
A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K Chowdhury, et al.
Medicinal Research Reviews|October 24, 2012
The generation, detection, and effects of reactive drug metabolitesAndrew V Stachulski, Thomas A Baillie, B Kevin Park, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 20, 2003
The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspectiveThorir D Bjornsson, John T Callaghan, Heidi J Einolf, et al.
Pageof 20