Showing results (251-260 of 288) with videos related to
Sort By:
Pageof 29
Journal of Medicinal Chemistry|September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|June 26, 2015
Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse ModelA Ghoshal, J M Rook, J W Dickerson, et al.Journal of Medicinal Chemistry|August 4, 2021
Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CLpro)Sang Hoon Han, Christopher M Goins, Tarun Arya, et al.Biological Psychiatry|November 13, 2012
Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activityJerri M Rook, Meredith J Noetzel, Wendy A Pouliot, et al.Journal of Medicinal Chemistry|December 4, 2003
Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithromboticsJames C Barrow, Philippe G Nantermet, Shaun R Stauffer, et al.Elife|October 19, 2021
scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolutionBilge E Öztürk, Molly E Johnson, Michael Kleyman, et al.Biorxiv : the Preprint Server for Biology|March 31, 2025
Uncovering synaptic and cellular nanoarchitecture of brain tissue via seamless in situ trimming and milling for cryo-electron tomographyJiying Ning, Jill R Glausier, Rangana Warshamanage, et al.Journal of Medicinal Chemistry|June 23, 2007
Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloidMatthew G Stanton, Shaun R Stauffer, Alison R Gregro, et al.Bioorganic & Medicinal Chemistry Letters|September 18, 2012
Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossoverJason T Manka, Paige N Vinson, Karen J Gregory, et al.Biorxiv : the Preprint Server for Biology|May 18, 2026
CpG island density predicts CBP/p300 dependency across 3D chromatin clustersMd Imdadul H Khan, Matthew S Chang, Yaw Asante, et al.Pageof 29