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Cell Reports|March 14, 2019
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar AffinityErin R Aho, Jing Wang, Rocco D Gogliotti, et al.The Journal of Pharmacology and Experimental Therapeutics|August 23, 2013
N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancementK J Gregory, E J Herman, A J Ramsey, et al.Genes & Development|February 2, 2023
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastomaKelly Mitchell, Samuel A Sprowls, Sonali Arora, et al.Nature Communications|November 14, 2025
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programsTreg Grubb, Pooneh Koochaki, Sayed Matar, et al.Journal of Medicinal Chemistry|August 17, 2013
Dihydrothiazolopyridone derivatives as a novel family of positive allosteric modulators of the metabotropic glutamate 5 (mGlu5) receptorJosé Manuel Bartolomé-Nebreda, Susana Conde-Ceide, Francisca Delgado, et al.Journal of Medicinal Chemistry|June 11, 2014
Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu₅)Mark Turlington, Chrysa Malosh, Jon Jacobs, et al.Journal of Medicinal Chemistry|September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretaseJames C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.Journal of Medicinal Chemistry|December 21, 2019
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic CoreJianhua Tian, Kevin B Teuscher, Erin R Aho, et al.Biorxiv : the Preprint Server for Biology|July 16, 2025
Combining Machine Learning and Multiplexed, In Situ Profiling to Engineer Cell Type and Behavioral SpecificityMichael J Leone, Robert van de Weerd, Ashley R Brown, et al.Journal of Emergency Nursing|July 14, 2010
The future of emergency medicineSandra M Schneider, Angela F Gardner, Larry D Weiss, et al.Pageof 29