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Showing results (251-260 of 272) with videos related to

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Journal of Medicinal Chemistry|August 4, 2009
Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagementHong C Shen, Fa-Xiang Ding, Siyi Wang, et al.
Bioorganic & Medicinal Chemistry Letters|December 15, 2010
Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole coreDong-Ming Shen, Edward J Brady, Mari R Candelore, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
Discovery of Spirocyclic Aldosterone Synthase Inhibitors as Potential Treatments for Resistant HypertensionWhitney L Petrilli, Scott B Hoyt, Clare London, et al.
Bioorganic & Medicinal Chemistry Letters|May 1, 2007
Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: synthesis, in vitro profile, molecular modeling studies, and in vivo experimentsChristopher F Thompson, Nazia Quraishi, Amjad Ali, et al.
Journal of Medicinal Chemistry|November 13, 2007
Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptorHong C Shen, Fa-Xiang Ding, Silvi Luell, et al.
Bioorganic & Medicinal Chemistry Letters|April 6, 2005
Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacyChristopher F Thompson, Nazia Quraishi, Amjad Ali, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2005
Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonistsDong-Ming Shen, Fengqi Zhang, Edward J Brady, et al.
Journal of Medicinal Chemistry|July 31, 2008
3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in miceGraeme Semple, Philip J Skinner, Tawfik Gharbaoui, et al.
Bioorganic & Medicinal Chemistry Letters|November 15, 2011
The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitorsThomas H Graham, Hong C Shen, Wensheng Liu, et al.
Bioorganic & Medicinal Chemistry Letters|November 6, 2016
Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effectsMatthew Lombardo, Kate Bender, Clare London, et al.
Pageof 28

Showing results (251-260 of 272) with videos related to

Sort By:
Pageof 28
Journal of Medicinal Chemistry|August 4, 2009
Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagementHong C Shen, Fa-Xiang Ding, Siyi Wang, et al.
Bioorganic & Medicinal Chemistry Letters|December 15, 2010
Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole coreDong-Ming Shen, Edward J Brady, Mari R Candelore, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
Discovery of Spirocyclic Aldosterone Synthase Inhibitors as Potential Treatments for Resistant HypertensionWhitney L Petrilli, Scott B Hoyt, Clare London, et al.
Bioorganic & Medicinal Chemistry Letters|May 1, 2007
Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: synthesis, in vitro profile, molecular modeling studies, and in vivo experimentsChristopher F Thompson, Nazia Quraishi, Amjad Ali, et al.
Journal of Medicinal Chemistry|November 13, 2007
Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptorHong C Shen, Fa-Xiang Ding, Silvi Luell, et al.
Bioorganic & Medicinal Chemistry Letters|April 6, 2005
Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacyChristopher F Thompson, Nazia Quraishi, Amjad Ali, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2005
Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonistsDong-Ming Shen, Fengqi Zhang, Edward J Brady, et al.
Journal of Medicinal Chemistry|July 31, 2008
3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in miceGraeme Semple, Philip J Skinner, Tawfik Gharbaoui, et al.
Bioorganic & Medicinal Chemistry Letters|November 15, 2011
The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitorsThomas H Graham, Hong C Shen, Wensheng Liu, et al.
Bioorganic & Medicinal Chemistry Letters|November 6, 2016
Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effectsMatthew Lombardo, Kate Bender, Clare London, et al.
Pageof 28