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Showing results (261-270 of 272) with videos related to

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Nature Microbiology|September 25, 2023
Host range, transmissibility and antigenicity of a pangolin coronavirusYixuan J Hou, Shiho Chiba, Sarah R Leist, et al.
Bioorganic & Medicinal Chemistry Letters|June 26, 2007
Agonist lead identification for the high affinity niacin receptor GPR109aTawfik Gharbaoui, Philip J Skinner, Young-Jun Shin, et al.
Bioorganic & Medicinal Chemistry Letters|February 8, 2017
Corrigendum to "Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects" [Bioorg. Med. Chem. Lett. 26 (2016) 5724-5728]Matthew Lombardo, Kate Bender, Clare London, et al.
Journal of Medicinal Chemistry|February 27, 2010
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidateHong C Shen, Fa-Xiang Ding, Subharekha Raghavan, et al.
Journal of Medicinal Chemistry|March 23, 2012
(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humansP Douglas Boatman, Brett Lauring, Thomas O Schrader, et al.
Bioorganic & Medicinal Chemistry Letters|May 25, 2005
Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activityCameron J Smith, Amjad Ali, James M Balkovec, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic AgonistsJason M Cox, Hong D Chu, Mariappan V Chelliah, et al.
Science Translational Medicine|August 24, 2012
Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppressionBrett Lauring, Andrew K P Taggart, James R Tata, et al.
Journal of Medicinal Chemistry|March 25, 2022
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of CancerWonsuk Chang, Michael D Altman, Charles A Lesburg, et al.
Cell Chemical Biology|October 27, 2019
From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9Whitney L Petrilli, Gregory C Adam, Roman S Erdmann, et al.
Pageof 28

Showing results (261-270 of 272) with videos related to

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Pageof 28
Nature Microbiology|September 25, 2023
Host range, transmissibility and antigenicity of a pangolin coronavirusYixuan J Hou, Shiho Chiba, Sarah R Leist, et al.
Bioorganic & Medicinal Chemistry Letters|June 26, 2007
Agonist lead identification for the high affinity niacin receptor GPR109aTawfik Gharbaoui, Philip J Skinner, Young-Jun Shin, et al.
Bioorganic & Medicinal Chemistry Letters|February 8, 2017
Corrigendum to "Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects" [Bioorg. Med. Chem. Lett. 26 (2016) 5724-5728]Matthew Lombardo, Kate Bender, Clare London, et al.
Journal of Medicinal Chemistry|February 27, 2010
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidateHong C Shen, Fa-Xiang Ding, Subharekha Raghavan, et al.
Journal of Medicinal Chemistry|March 23, 2012
(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humansP Douglas Boatman, Brett Lauring, Thomas O Schrader, et al.
Bioorganic & Medicinal Chemistry Letters|May 25, 2005
Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activityCameron J Smith, Amjad Ali, James M Balkovec, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic AgonistsJason M Cox, Hong D Chu, Mariappan V Chelliah, et al.
Science Translational Medicine|August 24, 2012
Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppressionBrett Lauring, Andrew K P Taggart, James R Tata, et al.
Journal of Medicinal Chemistry|March 25, 2022
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of CancerWonsuk Chang, Michael D Altman, Charles A Lesburg, et al.
Cell Chemical Biology|October 27, 2019
From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9Whitney L Petrilli, Gregory C Adam, Roman S Erdmann, et al.
Pageof 28