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Oncogene|July 8, 2018
Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir-bortezomib therapy to intensify endoplasmic reticulum stress-induced cell deathCharlotte E Johnson, Elaine A Dunlop, Sara Seifan, et al.
Autophagy|August 16, 2014
FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylationElaine A Dunlop, Sara Seifan, Tijs Claessens, et al.
Oncogene|March 26, 2025
Characterizing the tumor suppressor activity of FLCN in Birt-Hogg-Dubé syndrome cell models through transcriptomic and proteomic analysisRachel-Ann Jones, Elaine A Dunlop, Jesse D Champion, et al.
International Journal of Molecular Sciences|December 3, 2020
Distinctive Features of Orbital Adipose Tissue (OAT) in Graves' OrbitopathyLei Zhang, Anna Evans, Chris von Ruhland, et al.
European Journal of Human Genetics : EJHG|March 17, 2011
Determining the pathogenicity of patient-derived TSC2 mutations by functional characterization and clinical evidenceElaine A Dunlop, Kayleigh M Dodd, Stephen C Land, et al.
Oncogene|November 9, 2010
Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibilityR S Preston, A Philp, T Claessens, et al.
The Journal of Biological Chemistry|April 5, 2012
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signalingBruno D Fonseca, Graham H Diering, Michael A Bidinosti, et al.
Cancers|December 23, 2022
Drug Inhibition of Redox Factor-1 Restores Hypoxia-Driven Changes in Tuberous Sclerosis Complex 2 Deficient CellsJesse D Champion, Kayleigh M Dodd, Hilaire C Lam, et al.
Cancers|August 28, 2025
Targeting NRF2 and FSP1 to Overcome Ferroptosis Resistance in TSC2-Deficient and Cancer CellsTasmia Tahsin, Darius K McPhail, Jesse D Champion, et al.
Nature Cell Biology|August 20, 2013
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROSJiangwei Zhang, Jinhee Kim, Angela Alexander, et al.
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