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Showing results (341-350 of 418) with videos related to

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Journal of Medicinal Chemistry|October 5, 2001
Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1', a series of selective TNF-alpha converting enzyme inhibitors with potent cellular activity in the inhibition of TNF-alpha releaseC B Xue, X He, R L Corbett, et al.
Journal of Medicinal Chemistry|November 23, 2000
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitorsQ Han, C Dominguez, P F Stouten, et al.
Journal of Medicinal Chemistry|October 5, 2007
Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor XaDonald J P Pinto, Michael J Orwat, Stephanie Koch, et al.
Journal of Medicinal Chemistry|October 5, 2001
Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitorsW Yao, Z R Wasserman, M Chao, et al.
Journal of Medicinal Chemistry|January 14, 2000
Disubstituted indazoles as potent antagonists of the integrin alpha(v)beta(3)D G Batt, J J Petraitis, G C Houghton, et al.
ACS Medicinal Chemistry Letters|December 21, 2016
Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa InhibitorsNicholas R Wurtz, Brandon L Parkhurst, Wen Jiang, et al.
Bioorganic & Medicinal Chemistry Letters|February 19, 2013
Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitorsXiaojun Zhang, Peter W Glunz, Wen Jiang, et al.
Journal of Medicinal Chemistry|June 17, 2014
Discovery of 4-aryl-7-hydroxyindoline-based P2Y1 antagonists as novel antiplatelet agentsWu Yang, Yufeng Wang, Amy Lai, et al.
Journal of Medicinal Chemistry|March 13, 2015
Discovery of novel P1 groups for coagulation factor VIIa inhibition using fragment-based screeningDaniel L Cheney, Jeffrey M Bozarth, William J Metzler, et al.
Bioorganic & Medicinal Chemistry Letters|January 17, 2015
Pyridine and pyridinone-based factor XIa inhibitorsJames R Corte, Tianan Fang, Jon J Hangeland, et al.
Pageof 42

Showing results (341-350 of 418) with videos related to

Sort By:
Pageof 42
Journal of Medicinal Chemistry|October 5, 2001
Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1', a series of selective TNF-alpha converting enzyme inhibitors with potent cellular activity in the inhibition of TNF-alpha releaseC B Xue, X He, R L Corbett, et al.
Journal of Medicinal Chemistry|November 23, 2000
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitorsQ Han, C Dominguez, P F Stouten, et al.
Journal of Medicinal Chemistry|October 5, 2007
Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor XaDonald J P Pinto, Michael J Orwat, Stephanie Koch, et al.
Journal of Medicinal Chemistry|October 5, 2001
Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitorsW Yao, Z R Wasserman, M Chao, et al.
Journal of Medicinal Chemistry|January 14, 2000
Disubstituted indazoles as potent antagonists of the integrin alpha(v)beta(3)D G Batt, J J Petraitis, G C Houghton, et al.
ACS Medicinal Chemistry Letters|December 21, 2016
Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa InhibitorsNicholas R Wurtz, Brandon L Parkhurst, Wen Jiang, et al.
Bioorganic & Medicinal Chemistry Letters|February 19, 2013
Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitorsXiaojun Zhang, Peter W Glunz, Wen Jiang, et al.
Journal of Medicinal Chemistry|June 17, 2014
Discovery of 4-aryl-7-hydroxyindoline-based P2Y1 antagonists as novel antiplatelet agentsWu Yang, Yufeng Wang, Amy Lai, et al.
Journal of Medicinal Chemistry|March 13, 2015
Discovery of novel P1 groups for coagulation factor VIIa inhibition using fragment-based screeningDaniel L Cheney, Jeffrey M Bozarth, William J Metzler, et al.
Bioorganic & Medicinal Chemistry Letters|January 17, 2015
Pyridine and pyridinone-based factor XIa inhibitorsJames R Corte, Tianan Fang, Jon J Hangeland, et al.
Pageof 42