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Journal of Medicinal Chemistry
|
December 4, 2003
Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1)
James R Pruitt, Donald J P Pinto, Robert A Galemmo, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 2017
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
James R Corte, Wu Yang, Tianan Fang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 18, 2020
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Zilun Hu, Cailan Wang, Peter W Glunz, et al.
Journal of Medicinal Chemistry
|
January 11, 2014
Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors
Mimi L Quan, Pancras C Wong, Cailan Wang, et al.
ACS Medicinal Chemistry Letters
|
September 18, 2024
Discovery and Optimization of Aryl Piperidinone Ureas as Selective Formyl Peptide Receptor 2 Agonists
Nicholas R Wurtz, Pravin S Shirude, Daniel L Cheney, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 23, 2013
Discovery of diarylurea P2Y(1) antagonists with improved aqueous solubility
Tammy C Wang, Jennifer X Qiao, Charles G Clark, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 22, 2012
Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors
Michael M Miller, Yalei Liu, Ji Jiang, et al.
Journal of Medicinal Chemistry
|
October 3, 2003
Structure-based design of novel guanidine/benzamidine mimics: potent and orally bioavailable factor Xa inhibitors as novel anticoagulants
Patrick Y S Lam, Charles G Clark, Renhua Li, et al.
ACS Medicinal Chemistry Letters
|
January 8, 2019
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase
James A Johnson, George Tora, Zulan Pi, et al.
Journal of Medicinal Chemistry
|
May 28, 2025
The Discovery of C7-Substituted Norbornyl Bisamides as RXFP1 Small Molecule Agonists
Shun Su, Michael C Myers, Donna M Bilder, et al.
Page
of 42
Search research articles
Search
Showing results (371-380 of 418) with videos related to
Sort By:
Page
of 42
Journal of Medicinal Chemistry
|
December 4, 2003
Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1)
James R Pruitt, Donald J P Pinto, Robert A Galemmo, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 9, 2017
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
James R Corte, Wu Yang, Tianan Fang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 18, 2020
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Zilun Hu, Cailan Wang, Peter W Glunz, et al.
Journal of Medicinal Chemistry
|
January 11, 2014
Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors
Mimi L Quan, Pancras C Wong, Cailan Wang, et al.
ACS Medicinal Chemistry Letters
|
September 18, 2024
Discovery and Optimization of Aryl Piperidinone Ureas as Selective Formyl Peptide Receptor 2 Agonists
Nicholas R Wurtz, Pravin S Shirude, Daniel L Cheney, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 23, 2013
Discovery of diarylurea P2Y(1) antagonists with improved aqueous solubility
Tammy C Wang, Jennifer X Qiao, Charles G Clark, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 22, 2012
Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors
Michael M Miller, Yalei Liu, Ji Jiang, et al.
Journal of Medicinal Chemistry
|
October 3, 2003
Structure-based design of novel guanidine/benzamidine mimics: potent and orally bioavailable factor Xa inhibitors as novel anticoagulants
Patrick Y S Lam, Charles G Clark, Renhua Li, et al.
ACS Medicinal Chemistry Letters
|
January 8, 2019
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase
James A Johnson, George Tora, Zulan Pi, et al.
Journal of Medicinal Chemistry
|
May 28, 2025
The Discovery of C7-Substituted Norbornyl Bisamides as RXFP1 Small Molecule Agonists
Shun Su, Michael C Myers, Donna M Bilder, et al.
Page
of 42