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Bioorganic & Medicinal Chemistry Letters
|
December 13, 2005
Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
Radim Nencka, Ivan Votruba, Hubert Hrebabecký, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
July 7, 2015
The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design
Martin Klima, Adriana Baumlova, Dominika Chalupska, et al.
Nucleic Acids Research
|
January 12, 2022
Coronaviral RNA-methyltransferases: function, structure and inhibition
Radim Nencka, Jan Silhan, Martin Klima, et al.
Antiviral Research
|
August 9, 2020
Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses
Eva Konkolova, Milan Dejmek, Hubert Hřebabecký, et al.
Communications Biology
|
September 27, 2025
Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4-Xpf-Ercc1 nuclease complex in the Fanconi anaemia pathway
Jana Havlikova, Milan Dejmek, Andrea Huskova, et al.
Plos Pathogens
|
December 2, 2020
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein
Dhurvas Chandrasekaran Dinesh, Dominika Chalupska, Jan Silhan, et al.
Journal of Medicinal Chemistry
|
October 30, 2007
Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase
Radim Nencka, Ivan Votruba, Hubert Hrebabecký, et al.
European Journal of Medicinal Chemistry
|
November 30, 2025
Exploring advanced methodologies for NS5 methyltransferase targeted drug discovery
Tomáš Otava, Matúš Drexler, Petra Krafčíková, et al.
Antiviral Research
|
August 1, 2016
Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus
Luděk Eyer, Markéta Šmídková, Radim Nencka, et al.
Nucleic Acids Research
|
March 24, 2017
The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
Jakub Šebera, Yoshikazu Hattori, Daichi Sato, et al.
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Search research articles
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Showing results (21-30 of 93) with videos related to
Sort By:
Page
of 10
Bioorganic & Medicinal Chemistry Letters
|
December 13, 2005
Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
Radim Nencka, Ivan Votruba, Hubert Hrebabecký, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
July 7, 2015
The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design
Martin Klima, Adriana Baumlova, Dominika Chalupska, et al.
Nucleic Acids Research
|
January 12, 2022
Coronaviral RNA-methyltransferases: function, structure and inhibition
Radim Nencka, Jan Silhan, Martin Klima, et al.
Antiviral Research
|
August 9, 2020
Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses
Eva Konkolova, Milan Dejmek, Hubert Hřebabecký, et al.
Communications Biology
|
September 27, 2025
Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4-Xpf-Ercc1 nuclease complex in the Fanconi anaemia pathway
Jana Havlikova, Milan Dejmek, Andrea Huskova, et al.
Plos Pathogens
|
December 2, 2020
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein
Dhurvas Chandrasekaran Dinesh, Dominika Chalupska, Jan Silhan, et al.
Journal of Medicinal Chemistry
|
October 30, 2007
Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase
Radim Nencka, Ivan Votruba, Hubert Hrebabecký, et al.
European Journal of Medicinal Chemistry
|
November 30, 2025
Exploring advanced methodologies for NS5 methyltransferase targeted drug discovery
Tomáš Otava, Matúš Drexler, Petra Krafčíková, et al.
Antiviral Research
|
August 1, 2016
Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus
Luděk Eyer, Markéta Šmídková, Radim Nencka, et al.
Nucleic Acids Research
|
March 24, 2017
The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
Jakub Šebera, Yoshikazu Hattori, Daichi Sato, et al.
Page
of 10