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Radim Nencka

Showing results (81-90 of 93) with videos related to

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Journal of Medicinal Chemistry|May 21, 2021
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP)Markéta Pimková Polidarová, Petra Břehová, Martin Maxmilian Kaiser, et al.
Journal of Medicinal Chemistry|April 17, 2020
Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's DiseaseMichal Šála, Kristen R Hollinger, Ajit G Thomas, et al.
Cancer Research|January 20, 2023
SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid LeukemiaCourtney Chambers, Katerina Cermakova, Yuen San Chan, et al.
Journal of Medicinal Chemistry|December 23, 2016
Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical BiologyIvana Mejdrová, Dominika Chalupská, Pavla Plačková, et al.
Journal of Medicinal Chemistry|August 3, 2023
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-<i>b</i>]pyridazine Derivatives Identified by Scaffold HoppingPetra Břehová, Eva Řezníčková, Kryštof Škach, et al.
Angewandte Chemie (International Ed. in English)|August 28, 2019
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIßLea Kremer, Elisabeth Hennes, Alexandra Brause, et al.
Journal of Medicinal Chemistry|November 13, 2019
Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity CorrelationsBarbora Novotná, Lenka Vaneková, Martin Zavřel, et al.
Journal of Virology|August 18, 2017
Escape of Tick-Borne Flavivirus from 2'-<i>C</i>-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral FitnessLudek Eyer, Hirofumi Kondo, Darina Zouharova, et al.
Nature Communications|February 6, 2025
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia modelJan Dusek, Ivana Mejdrová, Klára Dohnalová, et al.
ACS Infectious Diseases|September 20, 2023
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric InhibitorsNicole L Inniss, Ján Kozic, Fengling Li, et al.
Pageof 10

Showing results (81-90 of 93) with videos related to

Sort By:
Pageof 10
Journal of Medicinal Chemistry|May 21, 2021
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP)Markéta Pimková Polidarová, Petra Břehová, Martin Maxmilian Kaiser, et al.
Journal of Medicinal Chemistry|April 17, 2020
Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's DiseaseMichal Šála, Kristen R Hollinger, Ajit G Thomas, et al.
Cancer Research|January 20, 2023
SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid LeukemiaCourtney Chambers, Katerina Cermakova, Yuen San Chan, et al.
Journal of Medicinal Chemistry|December 23, 2016
Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical BiologyIvana Mejdrová, Dominika Chalupská, Pavla Plačková, et al.
Journal of Medicinal Chemistry|August 3, 2023
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-<i>b</i>]pyridazine Derivatives Identified by Scaffold HoppingPetra Břehová, Eva Řezníčková, Kryštof Škach, et al.
Angewandte Chemie (International Ed. in English)|August 28, 2019
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIßLea Kremer, Elisabeth Hennes, Alexandra Brause, et al.
Journal of Medicinal Chemistry|November 13, 2019
Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity CorrelationsBarbora Novotná, Lenka Vaneková, Martin Zavřel, et al.
Journal of Virology|August 18, 2017
Escape of Tick-Borne Flavivirus from 2'-<i>C</i>-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral FitnessLudek Eyer, Hirofumi Kondo, Darina Zouharova, et al.
Nature Communications|February 6, 2025
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia modelJan Dusek, Ivana Mejdrová, Klára Dohnalová, et al.
ACS Infectious Diseases|September 20, 2023
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric InhibitorsNicole L Inniss, Ján Kozic, Fengling Li, et al.
Pageof 10