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Cell Stem Cell|May 5, 2023
Genetic engineering meets hematopoietic stem cell biology for next-generation gene therapySamuele Ferrari, Erika Valeri, Anastasia Conti, et al.
Aging Cell|March 5, 2019
An early-senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro-inflammatory programDaniela Gnani, Stefania Crippa, Lucrezia Della Volpe, et al.
Stem Cell Reports|May 14, 2021
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypesElisabeth Mangiameli, Anna Cecchele, Francesco Morena, et al.
Nature|December 1, 2006
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replicationRaffaella Di Micco, Marzia Fumagalli, Angelo Cicalese, et al.
Cancer Discovery|March 7, 2022
Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and RelapseValentina Gambacorta, Stefano Beretta, Martina Ciccimarra, et al.
The EMBO Journal|May 10, 2012
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesionsAnitha Suram, Jessica Kaplunov, Priyanka L Patel, et al.
Frontiers in Bioengineering and Biotechnology|October 17, 2024
A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34+ hematopoietic cells while allowing the detection of tumorigenic expansionPaolo Ritter, Stefania Oliveto, Chiara Cordiglieri, et al.
Nature Cell Biology|February 22, 2011
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancerRaffaella Di Micco, Gabriele Sulli, Miryana Dobreva, et al.
EMBO Molecular Medicine|October 9, 2023
The transcription factor HIF2α partakes in the differentiation block of acute myeloid leukemiaDaniela Magliulo, Matilde Simoni, Carolina Caserta, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|August 19, 2022
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCsStefania Crippa, Anastasia Conti, Valentina Vavassori, et al.
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