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Biotechnology and Bioengineering|April 22, 2018
An impurity characterization based approach for the rapid development of integrated downstream purification processesSteven M Timmick, Nicholas Vecchiarello, Chaz Goodwine, et al.Journal of Chromatography. A|July 26, 2018
Investigating the impact of aromatic ring substitutions on selectivity for a multimodal anion exchange prototype libraryJulie Robinson, Mark A Snyder, Chris Belisle, et al.Journal of Chromatography. A|January 28, 2012
Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulationsMelissa A Holstein, Wai Keen Chung, Siddharth Parimal, et al.Biotechnology Progress|January 23, 2026
Enhanced lentiviral vector recovery and separation using arginine hydrochloride with CIM QA monolithsAndrew J Kocot, Shivani Kulkarni, Ronit Ghosh, et al.Biotechnology and Bioengineering|May 14, 2019
A combined screening and in silico strategy for the rapid design of integrated downstream processes for process and product-related impurity removalNicholas Vecchiarello, Steven M Timmick, Chaz Goodwine, et al.Langmuir : the ACS Journal of Surfaces and Colloids|August 15, 2009
Utilization of lysozyme charge ladders to examine the effects of protein surface charge distribution on binding affinity in ion exchange systemsWai Keen Chung, Steven T Evans, Alexander S Freed, et al.Biotechnology Progress|June 10, 2024
High-throughput in silico workflow for optimization and characterization of multimodal chromatographic processesScott H Altern, Jessica Y Lyall, John P Welsh, et al.Biotechnology and Bioengineering|October 27, 2020
Identification of preferred multimodal ligand-binding regions on IgG1 F<sub>C</sub> using nuclear magnetic resonance and molecular dynamics simulationsRonak B Gudhka, Camille L Bilodeau, Scott A McCallum, et al.Biotechnology Progress|January 23, 2025
Coupling high-throughput and modeling approaches to streamline early-stage process development for biologicsJohn P Welsh, Scott H Altern, Jessica Y Lyall, et al.Journal of Chromatography. A|February 14, 2024
Mechanistic model-based characterization of size-exclusion-mixed-mode resins for removal of monoclonal antibody fragmentsScott H Altern, Andrew J Kocot, Jacob P LeBarre, et al.Pageof 14