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Blood|January 5, 2022
A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in miceAsim Saha, Sharon Hyzy, Tahirih Lamothe, et al.Blood|September 10, 2014
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioningBorja Saez, Francesca Ferraro, Rushdia Z Yusuf, et al.Blood|March 6, 2024
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia miceAsim Saha, Rahul Palchaudhuri, Leanne Lanieri, et al.Nature Communications|October 12, 2023
Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy modelNaoya Uchida, Ulana Stasula, Selami Demirci, et al.Cell Stem Cell|December 6, 2024
BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugateSelami Demirci, Jing Zeng, Rahul Palchaudhuri, et al.Pageof 3