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The Journal of Biological Chemistry
|
August 30, 2022
Engineering functional thermostable proteins using ancestral sequence reconstruction
Raine E S Thomson, Saskya E Carrera-Pacheco, Elizabeth M J Gillam
Advances in Pharmacology (San Diego, Calif.)
|
August 11, 2022
Use of engineered cytochromes P450 for accelerating drug discovery and development
Raine E S Thomson, Stephlina A D'Cunha, Martin A Hayes, et al.
Biochimica Et Biophysica Acta. Proteins and Proteomics
|
August 21, 2017
Determinants of thermostability in the cytochrome P450 fold
Kurt L Harris, Raine E S Thomson, Silja J Strohmaier, et al.
ACS Synthetic Biology
|
September 15, 2025
Reconstitution of Human Cytochrome P450 Activity using a <i>Leishmania</i> Cell-Free Protein Expression System
Wayne A Johnston, Raine E S Thomson, Juan Alfaro-Palma, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 4, 2024
Biocatalysis using Thermostable Cytochrome P450 Enzymes in Bacterial Membranes - Comparison of Metabolic Pathways with Human Liver Microsomes and Recombinant Human Enzymes
Ulrik Jurva, Ann-Sofie Sandinge, Jong Min Baek, et al.
The New Phytologist
|
June 1, 2022
Ancestral sequence reconstruction of the CYP711 family reveals functional divergence in strigolactone biosynthetic enzymes associated with gene duplication events in monocot grasses
Marcos H Vinde, Da Cao, Rebecca J Chesterfield, et al.
Molecular Biology and Evolution
|
May 31, 2022
Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates
Kurt L Harris, Raine E S Thomson, Yosephine Gumulya, et al.
The EMBO Journal
|
March 27, 2026
Thermostable ancestors enabled evolutionary diversification of promiscuous chemical defence enzymes
Raine E S Thomson, Yosephine Gumulya, Anthony W Bengochea, et al.
Angewandte Chemie (International Ed. in English)
|
January 1, 2024
Engineering Biocatalysts for the C-H Activation of Fatty Acids by Ancestral Sequence Reconstruction
Bethan S Jones, Connie M Ross, Gabriel Foley, et al.
Plos Computational Biology
|
October 24, 2022
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)
Gabriel Foley, Ariane Mora, Connie M Ross, et al.
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Search research articles
Search
Showing results (1-10 of 11) with videos related to
Sort By:
Page
of 2
The Journal of Biological Chemistry
|
August 30, 2022
Engineering functional thermostable proteins using ancestral sequence reconstruction
Raine E S Thomson, Saskya E Carrera-Pacheco, Elizabeth M J Gillam
Advances in Pharmacology (San Diego, Calif.)
|
August 11, 2022
Use of engineered cytochromes P450 for accelerating drug discovery and development
Raine E S Thomson, Stephlina A D'Cunha, Martin A Hayes, et al.
Biochimica Et Biophysica Acta. Proteins and Proteomics
|
August 21, 2017
Determinants of thermostability in the cytochrome P450 fold
Kurt L Harris, Raine E S Thomson, Silja J Strohmaier, et al.
ACS Synthetic Biology
|
September 15, 2025
Reconstitution of Human Cytochrome P450 Activity using a <i>Leishmania</i> Cell-Free Protein Expression System
Wayne A Johnston, Raine E S Thomson, Juan Alfaro-Palma, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 4, 2024
Biocatalysis using Thermostable Cytochrome P450 Enzymes in Bacterial Membranes - Comparison of Metabolic Pathways with Human Liver Microsomes and Recombinant Human Enzymes
Ulrik Jurva, Ann-Sofie Sandinge, Jong Min Baek, et al.
The New Phytologist
|
June 1, 2022
Ancestral sequence reconstruction of the CYP711 family reveals functional divergence in strigolactone biosynthetic enzymes associated with gene duplication events in monocot grasses
Marcos H Vinde, Da Cao, Rebecca J Chesterfield, et al.
Molecular Biology and Evolution
|
May 31, 2022
Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates
Kurt L Harris, Raine E S Thomson, Yosephine Gumulya, et al.
The EMBO Journal
|
March 27, 2026
Thermostable ancestors enabled evolutionary diversification of promiscuous chemical defence enzymes
Raine E S Thomson, Yosephine Gumulya, Anthony W Bengochea, et al.
Angewandte Chemie (International Ed. in English)
|
January 1, 2024
Engineering Biocatalysts for the C-H Activation of Fatty Acids by Ancestral Sequence Reconstruction
Bethan S Jones, Connie M Ross, Gabriel Foley, et al.
Plos Computational Biology
|
October 24, 2022
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)
Gabriel Foley, Ariane Mora, Connie M Ross, et al.
Page
of 2