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Rainer E Martin

Showing results (41-50 of 52) with videos related to

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Bioorganic & Medicinal Chemistry Letters|March 31, 2009
Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonistSong Feng, Minmin Yang, Zhenshan Zhang, et al.
JCI Insight|January 12, 2021
Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent mannerSara L Jepsen, Nicolai J Wewer Albrechtsen, Johanne A Windeløv, et al.
Bioorganic & Medicinal Chemistry Letters|July 9, 2013
Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonistsHenrietta Dehmlow, Rubén Alvarez Sánchez, Stephan Bachmann, et al.
Bioorganic & Medicinal Chemistry Letters|December 8, 2010
Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetesHans G F Richter, Gregory M Benson, Denise Blum, et al.
Nature Chemistry|November 23, 2023
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learningDavid F Nippa, Kenneth Atz, Remo Hohler, et al.
Journal of Medicinal Chemistry|September 26, 2015
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus MonkeysRainer E Martin, Johannes D Aebi, Benoit Hornsperger, et al.
Current Topics in Medicinal Chemistry|April 8, 2011
G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a surveyNicole A Kratochwil, Silvia Gatti-McArthur, Marius C Hoener, et al.
Bioconjugate Chemistry|November 2, 2023
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic PropertiesTatjana Sela, Mads Mansø, Michel Siegel, et al.
American Journal of Physiology. Endocrinology and Metabolism|September 11, 2019
Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in miceSara L Jepsen, Kaare V Grunddal, Nicolai J Wewer Albrechtsen, et al.
Nature Communications|November 25, 2025
Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimizationDavid F Nippa, Kenneth Atz, Yannick Stenzhorn, et al.
Pageof 6

Showing results (41-50 of 52) with videos related to

Sort By:
Pageof 6
Bioorganic & Medicinal Chemistry Letters|March 31, 2009
Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonistSong Feng, Minmin Yang, Zhenshan Zhang, et al.
JCI Insight|January 12, 2021
Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent mannerSara L Jepsen, Nicolai J Wewer Albrechtsen, Johanne A Windeløv, et al.
Bioorganic & Medicinal Chemistry Letters|July 9, 2013
Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonistsHenrietta Dehmlow, Rubén Alvarez Sánchez, Stephan Bachmann, et al.
Bioorganic & Medicinal Chemistry Letters|December 8, 2010
Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetesHans G F Richter, Gregory M Benson, Denise Blum, et al.
Nature Chemistry|November 23, 2023
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learningDavid F Nippa, Kenneth Atz, Remo Hohler, et al.
Journal of Medicinal Chemistry|September 26, 2015
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus MonkeysRainer E Martin, Johannes D Aebi, Benoit Hornsperger, et al.
Current Topics in Medicinal Chemistry|April 8, 2011
G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a surveyNicole A Kratochwil, Silvia Gatti-McArthur, Marius C Hoener, et al.
Bioconjugate Chemistry|November 2, 2023
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic PropertiesTatjana Sela, Mads Mansø, Michel Siegel, et al.
American Journal of Physiology. Endocrinology and Metabolism|September 11, 2019
Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in miceSara L Jepsen, Kaare V Grunddal, Nicolai J Wewer Albrechtsen, et al.
Nature Communications|November 25, 2025
Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimizationDavid F Nippa, Kenneth Atz, Yannick Stenzhorn, et al.
Pageof 6