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Elife|November 23, 2020
Differential impact of BTK active site inhibitors on the conformational state of full-length BTKRaji E Joseph, Neha Amatya, D Bruce Fulton, et al.
Journal of Molecular Biology|December 26, 2021
The Conformational State of the BTK Substrate PLCγ Contributes to Ibrutinib ResistanceRaji E Joseph, Jacques Lowe, D Bruce Fulton, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications|February 9, 2011
Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinaseRaji E Joseph, Nathaniel D Ginder, Julie A Hoy, et al.
Plos Computational Biology|March 25, 2016
Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family KinasesNikita Chopra, Thomas E Wales, Raji E Joseph, et al.
Biochemistry|December 13, 2023
Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine KinaseLauren E Kueffer, David Yin-Wei Lin, Neha Amatya, et al.
Protein Science : a Publication of the Protein Society|January 26, 2016
Dynamics of the Tec-family tyrosine kinase SH3 domainsJustin M Roberts, Sreya Tarafdar, Raji E Joseph, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications|February 3, 2012
Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structuresRaji E Joseph, Nathaniel D Ginder, Julie A Hoy, et al.
Science Signaling|August 29, 2013
Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinasesRaji E Joseph, Iivari Kleino, Thomas E Wales, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 9, 2019
Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinasesNeha Amatya, Thomas E Wales, Annie Kwon, et al.
Elife|December 27, 2024
Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemiaRaji E Joseph, Thomas E Wales, Sandrine Jayne, et al.
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