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Journal of Chemical Information and Modeling
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June 21, 2022
AI-Based Protein Structure Prediction in Drug Discovery: Impacts and Challenges
Michael Schauperl, Rajiah Aldrin Denny
Bioorganic & Medicinal Chemistry Letters
|
March 5, 2013
Recent developments in targeting protein misfolding diseases
Rajiah Aldrin Denny, Lori Krim Gavrin, Eddine Saiah
Journal of Medicinal Chemistry
|
October 19, 2012
Small molecules that target protein misfolding
Lori Krim Gavrin, Rajiah Aldrin Denny, Eddine Saiah
Journal of Chemical Information and Modeling
|
October 1, 2016
Computational Modeling of β-Secretase 1 (BACE-1) Inhibitors Using Ligand Based Approaches
Govindan Subramanian, Bharath Ramsundar, Vijay Pande, et al.
Journal of Computational Chemistry
|
October 27, 2016
Estimation of relative free energies of binding using pre-computed ensembles based on the single-step free energy perturbation and the site-identification by Ligand competitive saturation approaches
E Prabhu Raman, Sirish Kaushik Lakkaraju, Rajiah Aldrin Denny, et al.
Scientific Reports
|
November 17, 2017
Millisecond dynamics of BTK reveal kinome-wide conformational plasticity within the apo kinase domain
Mohammad M Sultan, Rajiah Aldrin Denny, Ray Unwalla, et al.
Frontiers in Molecular Biosciences
|
January 30, 2023
Recent applications of computational methods to allosteric drug discovery
Rajiv Gandhi Govindaraj, Sundar Thangapandian, Michael Schauperl, et al.
Scientific Reports
|
April 6, 2017
Markov modeling reveals novel intracellular modulation of the human TREK-2 selectivity filter
Matthew P Harrigan, Keri A McKiernan, Veerabahu Shanmugasundaram, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 11, 2021
Improved correction of F508del-CFTR biogenesis with a folding facilitator and an inhibitor of protein ubiquitination
Jennifer L Goeckeler-Fried, Rajiah Aldrin Denny, Disha Joshi, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 12, 2011
Discovery of indazoles as inhibitors of Tpl2 kinase
Yonghan Hu, Derek Cole, Rajiah Aldrin Denny, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
Journal of Chemical Information and Modeling
|
June 21, 2022
AI-Based Protein Structure Prediction in Drug Discovery: Impacts and Challenges
Michael Schauperl, Rajiah Aldrin Denny
Bioorganic & Medicinal Chemistry Letters
|
March 5, 2013
Recent developments in targeting protein misfolding diseases
Rajiah Aldrin Denny, Lori Krim Gavrin, Eddine Saiah
Journal of Medicinal Chemistry
|
October 19, 2012
Small molecules that target protein misfolding
Lori Krim Gavrin, Rajiah Aldrin Denny, Eddine Saiah
Journal of Chemical Information and Modeling
|
October 1, 2016
Computational Modeling of β-Secretase 1 (BACE-1) Inhibitors Using Ligand Based Approaches
Govindan Subramanian, Bharath Ramsundar, Vijay Pande, et al.
Journal of Computational Chemistry
|
October 27, 2016
Estimation of relative free energies of binding using pre-computed ensembles based on the single-step free energy perturbation and the site-identification by Ligand competitive saturation approaches
E Prabhu Raman, Sirish Kaushik Lakkaraju, Rajiah Aldrin Denny, et al.
Scientific Reports
|
November 17, 2017
Millisecond dynamics of BTK reveal kinome-wide conformational plasticity within the apo kinase domain
Mohammad M Sultan, Rajiah Aldrin Denny, Ray Unwalla, et al.
Frontiers in Molecular Biosciences
|
January 30, 2023
Recent applications of computational methods to allosteric drug discovery
Rajiv Gandhi Govindaraj, Sundar Thangapandian, Michael Schauperl, et al.
Scientific Reports
|
April 6, 2017
Markov modeling reveals novel intracellular modulation of the human TREK-2 selectivity filter
Matthew P Harrigan, Keri A McKiernan, Veerabahu Shanmugasundaram, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 11, 2021
Improved correction of F508del-CFTR biogenesis with a folding facilitator and an inhibitor of protein ubiquitination
Jennifer L Goeckeler-Fried, Rajiah Aldrin Denny, Disha Joshi, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 12, 2011
Discovery of indazoles as inhibitors of Tpl2 kinase
Yonghan Hu, Derek Cole, Rajiah Aldrin Denny, et al.
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of 2