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Chemico-Biological Interactions|January 19, 2010
Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profileMarta Moya, M José Gómez-Lechón, José V Castell, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 29, 2002
Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytesMaría José Gómez-Lechón, Enrique O'Connor, José Vicente Castell, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|October 2, 2002
Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involvedRamiro Jover, Roque Bort, M José Gómez-Lechón, et al.
Archives of Toxicology|July 22, 2026
The aryl hydrocarbon receptor is downregulated in MASLD while its activation attenuates steatosis in human hepatocytes through an IGFBP1-associated pathwayMarta Del Pozo-Medina, Polina Soluyanova, Eugenia Pareja, et al.
The Journal of Biological Chemistry|August 8, 2006
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cellsCelia P Martínez-Jiménez, M José Gómez-Lechón, José V Castell, et al.
Toxicology in Vitro : an International Journal Published in Association with BIBRA|November 6, 2003
Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytesGabriela Pérez, Beatriz Tabares, Ramiro Jover, et al.
Molecular Pharmacology|August 3, 2006
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1Celia P Martínez-Jiménez, José V Castell, M José Gómez-Lechón, et al.
Expert Opinion on Drug Metabolism & Toxicology|July 27, 2006
Hepatocyte cell lines: their use, scope and limitations in drug metabolism studiesJosé V Castell, Ramiro Jover, Celia P Martínez-Jiménez, et al.
Molecular Pharmacology|March 22, 2005
Transcriptional regulation of the human hepatic CYP3A4: identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein)Celia P Martínez-Jiménez, M José Gómez-Lechón, José V Castell, et al.
Alternatives to Laboratory Animals : ATLA|April 13, 2013
Can hepatoma cell lines be redifferentiated to be used in drug metabolism studies?Celia P Martínez-Jiménez, Ramiro Jover, Maria José Gómez-Lechón, et al.
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