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Journal of Medicinal Chemistry|September 17, 2004
Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific deliveryMichael L Miller, Elizabeth E Roller, Robert Y Zhao, et al.
Journal of Medicinal Chemistry|December 13, 2002
Tumor-specific novel taxoid-monoclonal antibody conjugatesIwao Ojima, Xudong Geng, Xinyuan Wu, et al.
Molecular Pharmaceutics|October 15, 2019
Optimizing Lysosomal Activation of Antibody-Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide LinkersPaulin L Salomon, Emily E Reid, Katie E Archer, et al.
Cancer Research|July 10, 2007
Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugateJoseph A Reddy, Elaine Westrick, Hari K R Santhapuram, et al.
Journal of Medicinal Chemistry|April 27, 2011
Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugatesRobert Y Zhao, Sharon D Wilhelm, Charlene Audette, et al.
Bioorganic & Medicinal Chemistry Letters|July 28, 2019
Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs)Emily E Reid, Katie E Archer, Manami Shizuka, et al.
Bioconjugate Chemistry|March 24, 2011
Disulfide-linked antibody-maytansinoid conjugates: optimization of in vivo activity by varying the steric hindrance at carbon atoms adjacent to the disulfide linkageBrenda A Kellogg, Lisa Garrett, Yelena Kovtun, et al.
Journal of Medicinal Chemistry|July 11, 2006
Semisynthetic maytansine analogues for the targeted treatment of cancerWayne C Widdison, Sharon D Wilhelm, Emily E Cavanagh, et al.
ACS Medicinal Chemistry Letters|August 16, 2019
Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody-Drug Conjugates (ADCs)Katie E Archer, Emily E Reid, Manami Shizuka, et al.
Blood Advances|April 18, 2018
A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cellsYelena Kovtun, Gregory E Jones, Sharlene Adams, et al.
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