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Clinical Pharmacology and Therapeutics|February 16, 2024
Scientific Review of the Proarrhythmic Risks of Oligonucleotide Therapeutics: Are Dedicated ICH S7B/E14 Studies Needed for Low-Risk Modalities?Yusheng Qu, Kim A Henderson, Tod A Harper, et al.Journal of Pharmacological and Toxicological Methods|June 3, 2021
Validation of using cardioplegic solutions for preserving cardiac function in isolated rabbit heart assaysZiva Arimura, BaoXi Gao, Mei Fang, et al.Journal of Pharmacological and Toxicological Methods|May 21, 2013
Safety pharmacology investigations in toxicology studies: an industry surveySimon Authier, Hugo M Vargas, Michael J Curtis, et al.Journal of Pharmacological and Toxicological Methods|July 7, 2020
Inotropic assessment in engineered 3D cardiac tissues using human induced pluripotent stem cell-derived cardiomyocytes in the BiowireTM II platformYusheng Qu, Nicole Feric, Isabella Pallotta, et al.Journal of Pharmacological and Toxicological Methods|June 11, 2025
Results from an EFPIA, JPMA, PhRMA industry survey on reopening and revamping the ICH S7A guidance on safety and secondary pharmacologyJean-Pierre Valentin, Katsuyoshi Chiba, Derek Leishman, et al.Pharmacology Research & Perspectives|February 19, 2015
Oxytocin does not directly alter cardiac repolarization in rabbit or human cardiac myocytesYusheng Qu, Mei Fang, BaoXi Gao, et al.Frontiers in Physiology|January 23, 2018
Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular TrabeculaeYusheng Qu, Guy Page, Najah Abi-Gerges, et al.Frontiers in Pharmacology|February 22, 2020
Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk AssessmentXin Zhou, Yusheng Qu, Elisa Passini, et al.Clinical and Translational Science|August 23, 2025
Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell-Derived Cardiomyocytes: Incubation Time MattersYusheng Qu, Wei Guo, Bin Wu, et al.Translational Oncology|July 23, 2019
Clinical Implications and Translation of an Off-Target Pharmacology Profiling Hit: Adenosine Uptake Inhibition In VitroHamid R Amouzadeh, Isaiah Dimery, Jonathan Werner, et al.Pageof 7