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Medchemcomm|August 16, 2018
Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin DJonathan D Low, Michael D Bartberger, Kui Chen, et al.
Toxicologic Pathology|May 4, 2012
Off-target platelet activation in macaques unique to a therapeutic monoclonal antibodyMichael J Santostefano, Jacqueline Kirchner, Christine Vissinga, et al.
Journal of Pharmacological and Toxicological Methods|May 30, 2008
Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologicsHugo M Vargas, Alan S Bass, Alexander Breidenbach, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|September 24, 2014
The concordance between nonclinical and phase I clinical cardiovascular assessment from a cross-company data sharing initiativeLorna Ewart, Mike Aylott, Mark Deurinck, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MSAshis K Saha, Xiang Yu, Jian Lin, et al.
Journal of Pharmacological and Toxicological Methods|May 10, 2023
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&AsEric I Rossman, Todd A Wisialowski, Hugo M Vargas, et al.
Chembiochem : a European Journal of Chemical Biology|October 4, 2002
Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonistsJames A Hendrix, Stephen J Shimshock, Gregory M Shutske, et al.
Journal of Pharmacological and Toxicological Methods|November 22, 2024
Predicting clinical outcomes from off-target receptor interactions using Secondary Intelligence™Will S Redfern, Chris E Pollard, Mark Holbrook, et al.
Environmental Health Perspectives|September 24, 2021
Key Characteristics of Cardiovascular ToxicantsLars Lind, Jesus A Araujo, Aaron Barchowsky, et al.
Journal of Pharmacological and Toxicological Methods|June 21, 2025
Current practices on the measurement of electrocardiogram and hemodynamic parameters in non-rodent species in regulatory safety assessment studiesJean-Pierre Valentin, Todd Bourcier, Xuan Chi, et al.
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