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Cell Death & Disease|August 22, 2019
The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancerMarina Kazantseva, Sunali Mehta, Ramona A Eiholzer, et al.
Journal of the American College of Cardiology|May 26, 2026
Anti-inflammatory effects of oral NLRP3 inhibition with ruvonoflast among individuals at elevated cardiovascular riskKausik K Ray, Nicholas Clarke, Peter Thornton, et al.
Nature Biotechnology|January 25, 2011
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexesMarcus Bantscheff, Carsten Hopf, Mikhail M Savitski, et al.
Journal of Medicinal Chemistry|May 12, 2017
Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)Emiliano Tamanini, Ildiko M Buck, Gianni Chessari, et al.
Journal of Medicinal Chemistry|July 29, 2015
Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAPGianni Chessari, Ildiko M Buck, James E H Day, et al.
The Journal of Pathology|July 2, 2019
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapyClaire S Reader, Sabari Vallath, Colin W Steele, et al.
Cancers|February 15, 2022
Microtentacle Formation in Ovarian CarcinomaJocelyn C Reader, Cong Fan, Eleanor Claire-Higgins Ory, et al.
British Journal of Cancer|February 12, 2022
Randomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancerDana M Roque, Eric R Siegel, Natalia Buza, et al.
Veterinary Pathology|July 11, 2013
Meeting report: Emerging respiratory viral infections and nonhuman primate case reportsV G Sasseville, J L Mankowski, A Baldessari, et al.
JCI Insight|February 10, 2025
Regulation of lung progenitor plasticity and repair by fatty acid oxidationQuetzalli D Angeles-Lopez, Jhonny Rodriguez-Lopez, Paula Agudelo Garcia, et al.
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