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Journal of Medicinal Chemistry|April 10, 2014
Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemiaMartha J Kelly, Sherrie Pietranico-Cole, J Douglas Larigan, et al.Bioorganic & Medicinal Chemistry Letters|May 13, 2014
Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitorsPaul Gillespie, Sherrie Pietranico-Cole, Michael Myers, et al.Journal of Medicinal Chemistry|March 19, 2011
Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetesYimin Qian, Stanley J Wertheimer, Mushtaq Ahmad, et al.The Journal of Biological Chemistry|January 29, 2005
Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the youngAnna L Gloyn, Stella Odili, Dorothy Zelent, et al.Molecular Cancer Therapeutics|May 18, 2005
Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicityCharles F Albright, Nilsa Graciani, Wei Han, et al.The New England Journal of Medicine|February 7, 2024
A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver FibrosisStephen A Harrison, Pierre Bedossa, Cynthia D Guy, et al.Pageof 5