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Biotechnology and Bioengineering|April 18, 2018
Stable miRNA overexpression in human CAP cells: Engineering alternative production systems for advanced manufacturing of biologics using miR-136 and miR-3074Benjamin L Weis, Nadine Guth, Simon Fischer, et al.Journal of Biotechnology|February 26, 2018
Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopySven Mathias, Simon Fischer, René Handrick, et al.Biochemical Pharmacology|September 10, 2008
Importance of Bak for celecoxib-induced apoptosisArndt-Christian Müller, René Handrick, Simon Johannes Elsaesser, et al.Engineering in Life Sciences|June 7, 2024
Stable overexpression of native and artificial miRNAs for the production of differentially fucosylated antibodies in CHO cellsPatrick Schlossbauer, Lukas Naumann, Florian Klingler, et al.Biotechnology Journal|February 26, 2019
CRISPR/Cas9-Mediated Knockout of MicroRNA-744 Improves Antibody Titer of CHO Production Cell LinesNadja Raab, Sven Mathias, Kerstin Alt, et al.Antioxidants & Redox Signaling|March 30, 2016
Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling HypoxiaJohann Matschke, Helena Riffkin, Diana Klein, et al.Scientific Reports|June 15, 2018
MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cellsMichael Kleemann, Helga Schneider, Kristian Unger, et al.Biotechnology and Bioengineering|October 14, 2015
Temperature-sensitive miR-483 is a conserved regulator of recombinant protein and viral vector production in mammalian cellsVerena V Emmerling, Simon Fischer, Fabian Stiefel, et al.Biotechnology and Bioengineering|October 22, 2019
Unraveling what makes a monoclonal antibody difficult-to-express: From intracellular accumulation to incomplete folding and degradation via ERADSven Mathias, Anna Wippermann, Nadja Raab, et al.Oncotarget|November 9, 2016
Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosisMichael Kleemann, Jeremias Bereuther, Simon Fischer, et al.Pageof 6