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Nature|July 1, 2026
TROP2 targeting reveals therapy-driven cell state dynamics in colorectal cancerNuria Vaquero-Siguero, Nikolaos Georgakopoulos, Maria C Puschhof, et al.
Nature Communications|June 9, 2021
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesisJoshua D G Leach, Nikola Vlahov, Petros Tsantoulis, et al.
JCO Precision Oncology|January 15, 2026
Functional Precision Medicine Using MicroOrganoSpheres for Treatment Response Prediction in Advanced Colorectal CancerRoán Gobits, Nikolai Schleußner, Gavin R Oliver, et al.
Journal of Experimental & Clinical Cancer Research : CR|February 29, 2024
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumorsKathryn A F Pennel, Phimmada Hatthakarnkul, Colin S Wood, et al.
Nature Communications|December 8, 2022
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive featuresDustin J Flanagan, Raheleh Amirkhah, David F Vincent, et al.
Cancer Discovery|December 17, 2020
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC ExpressionJohn R P Knight, Constantinos Alexandrou, George L Skalka, et al.
Hepatology (Baltimore, Md.)|November 2, 2023
Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCCAnna-Lena Scherr, Luisa Nader, Kaiyu Xu, et al.
Nature Genetics|January 8, 2021
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancerArafath K Najumudeen, Fatih Ceteci, Sigrid K Fey, et al.
Nature|November 25, 2025
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistanceMark White, Megan L Mills, Laura M Millett, et al.
EMBO Reports|July 23, 2025
Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapesDeclan Whyte, Sophie L Fisher, Christopher G J McKenzie, et al.
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