Showing results (1-10 of 16) with videos related to
Sort By:
Pageof 2
Biochemical Pharmacology|August 6, 2004
Differential inhibitor sensitivity between human recombinant and native photoreceptor cGMP-phosphodiesterases (PDE6s)Ji Zhang, Reshma Kuvelkar, Ping Wu, et al.Angewandte Chemie (International Ed. in English)|October 8, 2019
High-Throughput Bioassays using "Dip-and-Go" Multiplexed Electrospray Mass SpectrometryZhenwei Wei, Zhuoer Xie, Reshma Kuvelkar, et al.The Biochemical Journal|March 3, 2004
Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptorPeng Wang, Ji Zhang, Hong Bian, et al.Bioorganic & Medicinal Chemistry Letters|February 23, 2023
Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methodsSymon Gathiaka, Rachel L Palte, Sung-Sau So, et al.Bioorganic & Medicinal Chemistry Letters|December 3, 2014
Discovery of potent iminoheterocycle BACE1 inhibitorsJohn P Caldwell, Robert D Mazzola, James Durkin, et al.Bioorganic & Medicinal Chemistry Letters|March 30, 2010
Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterizationJared Cumming, Suresh Babu, Ying Huang, et al.Journal of Medicinal Chemistry|January 2, 2010
Discovery of cyclic acylguanidines as highly potent and selective beta-site amyloid cleaving enzyme (BACE) inhibitors: Part I--inhibitor design and validationZhaoning Zhu, Zhong-Yue Sun, Yuanzan Ye, et al.Journal of Medicinal Chemistry|November 3, 2018
Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine MoietyMihirbaran Mandal, Kaushik Mitra, Diane Grotz, et al.Bioorganic & Medicinal Chemistry Letters|March 7, 2012
Structure based design of iminohydantoin BACE1 inhibitors: identification of an orally available, centrally active BACE1 inhibitorJared N Cumming, Elizabeth M Smith, Lingyan Wang, et al.Science Translational Medicine|November 4, 2016
The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patientsMatthew E Kennedy, Andrew W Stamford, Xia Chen, et al.Pageof 2