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Scientific Reports|November 13, 2021
A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell linesReto Eggenschwiler, Thomas Gschwendtberger, Christian Felski, et al.
Hepatology Communications|September 29, 2025
iPSC-based hepatic organoids reveal a heterozygous MYO5B variant as driver of intrahepatic cholestasisMalte Sgodda, Evelyn Gebel, Lennart Dignas, et al.
Biomaterials|December 3, 2013
Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapyMania Ackermann, Nico Lachmann, Susann Hartung, et al.
Nucleic Acids Research|August 14, 2025
PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activityReto Eggenschwiler, Thomas Hoffmann, Oleg Dmytrenko, et al.
Stem Cell Research|December 31, 2016
MicroRNA-29 impairs the early phase of reprogramming process by targeting active DNA demethylation enzymes and Wnt signalingMariane Serra Fráguas, Reto Eggenschwiler, Jeannine Hoepfner, et al.
Stem Cells Translational Medicine|August 9, 2013
Sustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapyReto Eggenschwiler, Komal Loya, Guangming Wu, et al.
Human Molecular Genetics|May 21, 2019
Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutationsFranziska Bursch, Norman Kalmbach, Maximilian Naujock, et al.
Tissue Engineering. Part A|October 16, 2014
Bronchoalveolar sublineage specification of pluripotent stem cells: effect of dexamethasone plus cAMP-elevating agents and keratinocyte growth factorKatherina Katsirntaki, Christina Mauritz, Ruth Olmer, et al.
Scientific Reports|December 3, 2016
Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickaseReto Eggenschwiler, Mohsen Moslem, Mariane Serra Fráguas, et al.
Cell Reports. Medicine|May 4, 2024
Targeting low levels of MIF expression as a potential therapeutic strategy for ALSLeenor Alfahel, Thomas Gschwendtberger, Velina Kozareva, et al.
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