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Nature Communications|September 17, 2017
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagyRhianna C Laker, Joshua C Drake, Rebecca J Wilson, et al.The Journal of Biological Chemistry|March 20, 2014
A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivoRhianna C Laker, Peng Xu, Karen A Ryall, et al.Nature Communications|May 21, 2025
GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic β-cell function in obese male miceRhianna C Laker, Shaun Egolf, Sarah Will, et al.Nature Metabolism|June 2, 2020
Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesisMichelle L Boland, Rhianna C Laker, Karly Mather, et al.Science Advances|October 20, 2021
Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscleBrendan M Gabriel, Ali Altıntaş, Jonathon A B Smith, et al.Molecular Metabolism|November 15, 2021
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitriesBrandon B Boland, Rhianna C Laker, Siobhan O'Brien, et al.Proceedings of the National Academy of Sciences of the United States of America|September 8, 2021
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagyJoshua C Drake, Rebecca J Wilson, Rhianna C Laker, et al.Pageof 3