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Cell|April 3, 2020
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas CancerMarcus Ruscetti, John P Morris, Riccardo Mezzadra, et al.
Nature Medicine|December 5, 2018
Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancersWouter Scheper, Sander Kelderman, Lorenzo F Fanchi, et al.
Nature Aging|January 24, 2024
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunctionCorina Amor, Inés Fernández-Maestre, Saria Chowdhury, et al.
Nature|August 17, 2017
Identification of CMTM6 and CMTM4 as PD-L1 protein regulatorsRiccardo Mezzadra, Chong Sun, Lucas T Jae, et al.
Blood|January 10, 2025
α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemiaScott E Millman, Almudena Chaves-Perez, Sudha Janaki-Raman, et al.
Cancer Discovery|April 28, 2025
Direct Inhibition of RAS Reveals the Features of Oncogenic Signaling Driven by RAS G12 and Q61 MutationsMichelangelo Marasco, Dinesh Kumar, Santiago Garcia Borrego, et al.
Cell|July 16, 2019
Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity ThresholdDavid W Vredevoogd, Thomas Kuilman, Maarten A Ligtenberg, et al.
The Journal of Clinical Investigation|September 15, 2022
Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockadeArnab Ghosh, Judith Michels, Riccardo Mezzadra, et al.
The New England Journal of Medicine|July 20, 2016
Mutations Associated with Acquired Resistance to PD-1 Blockade in MelanomaJesse M Zaretsky, Angel Garcia-Diaz, Daniel S Shin, et al.
Cancer Discovery|November 10, 2022
Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal CancerRona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, et al.
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