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Fundamental & Clinical Pharmacology|February 22, 2019
A population analysis of the DGAT1 inhibitor GSK3008356 and its effect on endogenous and meal-induced triglyceride turnover in healthy subjectsMalek Okour, Richard A Brigandi, David TeneroCurrent Opinion in Pharmacology|May 14, 2004
Emerging therapeutic targets in psoriasisAndrew I Bayliffe, Richard A Brigandi, H Jeffrey Wilkins, et al.Clinical Pharmacology in Drug Development|January 17, 2019
A Phase 1 Randomized, Placebo-Controlled Trial With a Topical Inhibitor of Stearoyl-Coenzyme A Desaturase 1 Under Occluded and Nonoccluded ConditionsRichard A Brigandi, John Zhu, Amy A Murnane, et al.Clinical Pharmacology in Drug Development|April 6, 2019
First-in-Human Pharmacokinetics and Safety Study of GSK3008356, a Selective DGAT1 Inhibitor, in Healthy VolunteersMalek Okour, Angela Gress, Xinyi Zhu, et al.Clinical Pharmacology in Drug Development|June 23, 2015
Intravenous Pharmacokinetics, Local Tolerability, and Hemolysis of an SBE7-β-Cyclodextrin Formulation of the Neurokinin-1 Receptor Antagonist VestipitantRichard A Brigandi, Steven F Russ, Chantal Petit, et al.Blood|July 31, 2014
The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myelomaAndrew Spencer, Sung-Soo Yoon, Simon J Harrison, et al.American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation|February 1, 2016
A Novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (GSK1278863) for Anemia in CKD: A 28-Day, Phase 2A Randomized TrialRichard A Brigandi, Brendan Johnson, Coreen Oei, et al.Journal of Medicinal Chemistry|February 19, 2009
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st centuryPaul M O'Neill, B Kevin Park, Alison E Shone, et al.Journal of Medicinal Chemistry|March 17, 2009
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquinePaul M O'Neill, Alison E Shone, Deborah Stanford, et al.Pageof 1