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The Journal of Cell Biology|March 19, 2025
Structural characterization and inhibition of the interaction between ch-TOG and TACC3James Shelford, Selena G Burgess, Elena Rostkova, et al.ACS Chemical Biology|October 19, 2017
Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based ApproachesPatrick J McIntyre, Patrick M Collins, Lukáš Vrzal, et al.Journal of Cell Science|March 19, 2020
EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7Laura O'Regan, Giancarlo Barone, Rozita Adib, et al.Bioorganic & Medicinal Chemistry Letters|August 23, 2015
7-(Pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine-based derivatives for kinase inhibition: Co-crystallisation studies with Aurora-A reveal distinct differences in the orientation of the pyrazole N1-substituentVassilios Bavetsias, Yolanda Pérez-Fuertes, Patrick J McIntyre, et al.ACS Medicinal Chemistry Letters|April 16, 2020
Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET<sup>V804M</sup> KinaseRebecca Newton, Bohdan Waszkowycz, Chitra Seewooruthun, et al.Journal of Medicinal Chemistry|March 13, 2012
Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activityPaolo Innocenti, Kwai-Ming J Cheung, Savade Solanki, et al.Nature Communications|November 17, 2025
RAF inhibitors activate the integrated stress response by direct activation of GCN2Rebecca Gilley, Andrew M Kidger, Graham Neill, et al.Open Biology|January 19, 2022
Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cellsPoonam Kakade, Hina Ojha, Olawale G Raimi, et al.Cell Reports|December 21, 2017
Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell CycleGabriele Büchel, Anne Carstensen, Ka-Yan Mak, et al.Journal of Medicinal Chemistry|October 13, 2010
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterizationDaniel K Whelligan, Savade Solanki, Dawn Taylor, et al.Pageof 13